ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CELSR2
Previous Symbol	EGFL2
Symbol Alias	KIAA0279, MEGF3, Flamingo1, CDHF10
Approved Name	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
Previous Name	cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog
Location	1p13.3
Position	chr1:109792641-109818378, +
External Links	HGNC: 3231 Entrez Gene: 1952 Ensembl: ENSG00000143126 UCSC: uc001dxa.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_1	chr1:109103606-109682244 (NCBI36 / hg18)	578639	1p13.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0022407	regulation of cell-cell adhesion	Biological Process		2
GO:0021999	neural plate anterior/posterior regionalization	Biological Process		1
GO:0048813	dendrite morphogenesis	Biological Process		8
GO:0001764	neuron migration	Biological Process		21
GO:0004930	G-protein coupled receptor activity	Molecular Function	NAS[10907856]	236
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005737	cytoplasm	Cellular Component		690
GO:0007218	neuropeptide signaling pathway	Biological Process		17
GO:0016021	integral to membrane	Cellular Component	NAS[10907856]	845
GO:0016055	Wnt receptor signaling pathway	Biological Process		20
GO:0021591	ventricular system development	Biological Process		2
GO:0005886	plasma membrane	Cellular Component		772
GO:0006355	regulation of transcription, DNA-dependent	Biological Process		158
GO:0007156	homophilic cell adhesion	Biological Process		27
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	NAS[10907856]	72

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CELSR2 (count: 7)

Gene Symbol	Pathway Count	Pathway List
BAI3	5	G-protein coupled receptor activity; neuropeptide signaling pathway; integral to membrane; plasma membrane; G-protein coupled receptor signaling pathway;
GPR123	5	G-protein coupled receptor activity; cytoplasm; integral to membrane; plasma membrane; G-protein coupled receptor signaling pathway;
GPR144	5	G-protein coupled receptor activity; neuropeptide signaling pathway; integral to membrane; plasma membrane; G-protein coupled receptor signaling pathway;
LPHN3	5	G-protein coupled receptor activity; neuropeptide signaling pathway; integral to membrane; plasma membrane; G-protein coupled receptor signaling pathway;
CDH6	5	calcium ion binding; cytoplasm; integral to membrane; plasma membrane; homophilic cell adhesion;
DSC3	5	calcium ion binding; cytoplasm; integral to membrane; plasma membrane; homophilic cell adhesion;
SORT1	5	cytoplasm; neuropeptide signaling pathway; integral to membrane; plasma membrane; G-protein coupled receptor signaling pathway;

Genes shared at least 2 KEGG pathways with CELSR2 (count: 0)

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Region: chr1:109792641..109818378 View in gBrowse