ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CHN2
Symbol Alias	ARHGAP3, RhoGAP3
Approved Name	chimerin 2
Previous Name	"chimerin (chimaerin) 2"
Name Alias	"beta chimerin", "chimaerin 2"
Location	7p15.3
Position	chr7:29161890-29553944, 1
External Links	HGNC: 1944 Entrez Gene: 1124 Ensembl: ENSG00000106069 UCSC: uc003szz.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_95	chr7:28982601-29309947 (NCBI Build 35 (hg17))	327347	7p15.1	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005070	SH3/SH2 adaptor activity	molecular function	TAS[8175705]	7
GO:0005829	cytosol	cellular component	TAS	485
GO:0046872	metal ion binding	molecular function	IEA	200
GO:0043547	positive regulation of GTPase activity	biological process	TAS[7614486]	12
GO:0051056	regulation of small GTPase mediated signal transduction	biological process	TAS	32
GO:0007264	small GTPase mediated signal transduction	biological process	TAS	65
GO:0005096	GTPase activator activity	molecular function	IEA	28
GO:0016020	membrane	cellular component	IEA	155

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CHN2 (count: 3)

Gene Symbol	Pathway Count	Pathway List
ARHGDIG	5	cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; GTPase activator activity; membrane;
TIAM2	5	cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; GTPase activator activity; membrane;
ARHGEF12	5	cytosol; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; GTPase activator activity; membrane;

Genes shared at least 2 KEGG pathways with CHN2 (count: 0)

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Region: chr7:29161890..29553944 View in gBrowse