ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005096
Name	GTPase activator activity
Type	molecular function
No. of Genes in ADHDgene	28
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 28)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
RGS18	regulator of G-protein signaling 18	1q31.2	1(0/1/0)	IBA
ARRB1	arrestin, beta 1	11q13	2(1/1/0)	IMP[15611106]
TIAM2	T-cell lymphoma invasion and metastasis 2	6q25	1(0/0/1)	IEA

Genes from other sources (count: 25)

Approved Symbol	Approved Name	Source	Evidence[PMID]
RABEP2	rabaptin, RAB GTPase binding effector protein 2	Mapped by LD-proxy	IEA
ARHGAP32	Rho GTPase activating protein 32	Mapped by significant region	IEA
RGS11	regulator of G-protein signaling 11	Mapped by significant region	IBA
FAM13A	family with sequence similarity 13, member A	Mapped by CNV	IEA
RANBP1	RAN binding protein 1	Mapped by CNV	IEA
ARHGAP20	Rho GTPase activating protein 20	Mapped by significant region	IEA
GAPVD1	GTPase activating protein and VPS9 domains 1	Mapped by significant region	IEA
RGS3	regulator of G-protein signaling 3	Mapped by significant region	IBA
RGS16	regulator of G-protein signaling 16	Mapped by significant region	IBA
VPS9D1	VPS9 domain containing 1	Mapped by significant region	IEA
AXIN1	axin 1	Mapped by significant region	IBA
ELMOD1	ELMO/CED-12 domain containing 1	Mapped by significant region	IDA[17452337]
GARNL3	GTPase activating Rap/RanGAP domain-like 3	Mapped by significant region	IEA
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	Mapped by significant region	IEA
TSC2	tuberous sclerosis 2	Mapped by significant region	IDA[9045618]
RGS8	regulator of G-protein signaling 8	Mapped by significant region	IBA
ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma	Mapped by significant region	IEA
RIN1	Ras and Rab interactor 1	Mapped by significant region	IEA
ARHGAP42	Rho GTPase activating protein 42	Mapped by significant region	IEA
SIPA1	signal-induced proliferation-associated 1	Mapped by significant region	TAS[9346962]
ARHGAP11A	Rho GTPase activating protein 11A	Mapped by CNV; Mapped by significant region	IEA
ARHGAP11B	Rho GTPase activating protein 11B	Mapped by CNV; Mapped by significant region	IEA
ARHGAP18	Rho GTPase activating protein 18	Mapped by CNV; Mapped by significant region	IEA
RABGAP1	RAB GTPase activating protein 1	Mapped by significant region	TAS[10202141]
CHN2	chimerin 2	Mapped by CNV	IEA