ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol HTR4
Symbol Alias 5-HT4
Approved Name 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
Previous Name "5-hydroxytryptamine (serotonin) receptor 4"
Location 5q31-q33
Position chr5:147830595-148056798, -1
External Links HGNC: 5299
Entrez Gene: 3360
Ensembl: ENSG00000164270
UCSC: uc021yfj.1
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Li J, 2006(b) haplotype C/G from variants 83097 C>T/83198 A>G TDT P-value=0.003, X2=8.783; haplotype C/G/C from 83097 C> T/83198 A>G/-36 C>T TDT P-value=0.016, X2=5.762; HTR4 gene may play a role in the genetic predisposition to ADHD Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 3)

Gene related regions (count: 0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)


Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with HTR4 (count: 12)

Genes shared at least 2 KEGG pathways with HTR4 (count: 28)

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Region: chr5:147830595..148056798 View in gBrowse
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