ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol CHRNA7
Approved Name cholinergic receptor, nicotinic, alpha 7
Previous Name cholinergic receptor, nicotinic, alpha polypeptide 7
Location 15q13.3
Position chr15:32322691-32464722, +
External Links HGNC: 1960
Entrez Gene: 1139
Ensembl: ENSG00000175344
UCSC: uc001zft.2
No. of Studies 2 (significant: 0; non-significant: 1; trend: 1)
Source Literature-origin; Mapped by CNV; Mapped by significant region

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Kent L, 2001(a) The extended Transmission Disequilibrium Test analyses demonstrated no evidence that variation at the microsatellite markers D15S1360, D15S1043, and D15S165 influences susceptibility to ADHD. Non-significant
Stergiakouli E., 2012 was affected by six large duplications in case subjects (none in comparison subjects), and SNPs in the gene had a gene-wide p value of 0.0002 for association in the GWAS. Trend

Gene related SNPs (count: 0)

Gene related CNVs (count: 5)

Gene related other variant (count: 3)

Gene related regions (count: 2)

Gene related GO terms (count: 26)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 26)

Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with CHRNA7 (count: 14)

Genes shared at least 2 KEGG pathways with CHRNA7 (count: 30)

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Region: chr15:32322691..32464722 View in gBrowse
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