ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol GRM5
Symbol Alias MGLUR5, GPRC1E, mGlu5
Approved Name glutamate receptor, metabotropic 5
Location 11q14.3
Position chr11:88237744-88799113, -1
External Links HGNC: 4597
Entrez Gene: 2915
Ensembl: ENSG00000168959
UCSC: uc001pcq.3
No. of Studies 2 (significant: 1; non-significant: 0; trend: 1)
Source Literature-origin; Mapped by Literature SNP; Mapped by CNV; Mapped by significant region

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Hinney, A., 2011 This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. Trend
Elia, J., 2012 This gene was found directly affected by CNVRs overrepresented in individuals with ADHD. Significant

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)


Gene related CNVs (count: 2)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Gene related GO terms (count: 19)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 19)


Gene related KEGG pathways (count: 5)

Genes shared at least 5 GO terms with GRM5 (count: 10)

Genes shared at least 2 KEGG pathways with GRM5 (count: 50)

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Region: chr11:88237744..88799113 View in gBrowse
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