ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol CACNA1C
Previous Symbol CCHL1A1, CACNL1A1
Symbol Alias Cav1.2, CACH2, CACN2, TS, LQT8
Approved Name calcium channel, voltage-dependent, L type, alpha 1C subunit
Location 12p13.3
Position chr12:2079952-2802108, 1
External Links HGNC: 1390
Entrez Gene: 775
Ensembl: ENSG00000151067
UCSC: uc001qjy.3
No. of Studies 3 (significant: 0; non-significant: 3; trend: 0)
Source Literature-origin; Mapped by Literature SNP; Mapped by PBA pathway

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Landaas ET, 2011 no SNP showed evidence of association Non-significant
PGC, 2013 No significant association was reported in this study. Non-significant
Schimmelmann, B. G.,2013 No evidence for association was found with ADHD for the investigated SNPs within this gene, which were found to be genome-wide significant for BD in international GWAS Non-significant

Gene related SNPs (count: 31)

Literature-origin SNPs (count: 3)

LD-proxies (count: 28)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 35)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 35)

Gene related KEGG pathways (count: 5)

Genes shared at least 5 GO terms with CACNA1C (count: 52)

Genes shared at least 2 KEGG pathways with CACNA1C (count: 36)

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Region: chr12:2079952..2802108 View in gBrowse
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