ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol STX1A
Previous Symbol STX1
Symbol Alias HPC-1, p35-1
Approved Name syntaxin 1A (brain)
Location 7q11.2
Position chr7:73113536-73134002, -1
External Links HGNC: 11433
Entrez Gene: 6804
Ensembl: ENSG00000106089
UCSC: uc003tyx.3
No. of Studies 3 (significant: 2; non-significant: 1; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Sanchez-Mora, C., 2012 STX1A was found associated with ADHD only in adults (p=0.0041; OR=1.28 (1.08-1.51)) Significant
Brookes K, 2006 UNPHASED TDT P-value=0.146, global P-value=0.485, WHAP TDT P_sum P-value=0.192, no SNP with nominal P-value<0.05 located in this gene Non-significant
Brookes KJ, 2005 (b) 1 SNP showed nominal significance in TDT analysis Significant

Gene related SNPs (count: 10)

Literature-origin SNPs (count: 5)

LD-proxies (count: 5)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 35)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 35)


Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with STX1A (count: 37)

Genes shared at least 2 KEGG pathways with STX1A (count: 0)

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Region: chr7:73113536..73134002 View in gBrowse
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