ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006112
Name energy reserve metabolic process
Type biological process
No. of Genes in ADHDgene  31
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 9)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) TAS
STX1A syntaxin 1A (brain) 7q11.2 3(2/1/0) TAS
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 2(0/2/0) TAS
ADRB3 adrenoceptor beta 3 8p12 2(0/2/0) TAS[1718744]
ADRA2C adrenoceptor alpha 2C 4p16.3 7(2/4/1) TAS
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) TAS
MC4R melanocortin 4 receptor 18q22 1(0/1/0) IEA
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1) TAS
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 3(0/3/0) TAS

Genes from other sources Help (count: 22)

Approved Symbol Approved Name Source Evidence[PMID]
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) Mapped by significant region TAS
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
GNG3 guanine nucleotide binding protein (G protein), gamma 3 Mapped by significant region TAS
GFPT2 glutamine-fructose-6-phosphate transaminase 2 Mapped by CNV TAS[10198162]
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit Mapped by PBA pathway TAS
INS insulin Mapped by Literature SNP TAS
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit Mapped by PBA pathway TAS
ADCY4 adenylate cyclase 4 Mapped by significant region TAS
SEC11C SEC11 homolog C (S. cerevisiae) Mapped by significant region TAS
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway TAS
ADCY9 adenylate cyclase 9 Mapped by significant region TAS
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit Mapped by CNV TAS
ACACA acetyl-CoA carboxylase alpha Mapped by CNV TAS
STK11 serine/threonine kinase 11 Mapped by CNV TAS
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) Mapped by LD-proxy TAS
GNG10 guanine nucleotide binding protein (G protein), gamma 10 Mapped by significant region TAS
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit Mapped by significant region; Mapped by PBA pathway TAS
ADCY3 adenylate cyclase 3 Mapped by LD-proxy TAS
GNG13 guanine nucleotide binding protein (G protein), gamma 13 Mapped by significant region TAS
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region TAS
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV TAS