ADHDgene Database

Gene Report

Basic Info

Approved Symbol	STX3
Previous Symbol	STX3A
Approved Name	syntaxin 3
Previous Name	syntaxin 3A
Location	11q12.1
Position	chr11:59522532-59573355, +
External Links	HGNC: 11438 Entrez Gene: 6809 Ensembl: ENSG00000166900 UCSC: uc001nog.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043005	neuron projection	Cellular Component		35
GO:0050544	arachidonic acid binding	Molecular Function		1
GO:0031201	SNARE complex	Cellular Component		13
GO:0034599	cellular response to oxidative stress	Biological Process	IDA[16551573]	5
GO:0042581	specific granule	Cellular Component	IDA[18588921]	5
GO:0042582	azurophil granule	Cellular Component	IDA[18588921]	2
GO:0016021	integral to membrane	Cellular Component		845
GO:0016324	apical plasma membrane	Cellular Component	IDA[16339081]	51
GO:0030426	growth cone	Cellular Component		20
GO:0031175	neuron projection development	Biological Process		10
GO:0005773	vacuole	Cellular Component	TAS[16339081]	2
GO:0005911	cell-cell junction	Cellular Component	IDA[15576373]	20
GO:0005484	SNAP receptor activity	Molecular Function		13
GO:0005515	protein binding	Molecular Function	IPI[17693260]	910
GO:0006887	exocytosis	Biological Process		14
GO:0006944	cellular membrane fusion	Biological Process		8
GO:0006836	neurotransmitter transport	Biological Process		5
GO:0006886	intracellular protein transport	Biological Process		43

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04130	SNARE interactions in vesicular transport	20

Genes shared at least 5 GO terms with STX3 (count: 6)

Gene Symbol	Pathway Count	Pathway List
STX4	8	SNARE complex; specific granule; integral to membrane; vacuole; SNAP receptor activity; protein binding; neurotransmitter transport; intracellular protein transport;
SNAP23	6	neuron projection; specific granule; azurophil granule; protein binding; exocytosis; cellular membrane fusion;
STX1A	6	neuron projection; SNARE complex; integral to membrane; SNAP receptor activity; protein binding; intracellular protein transport;
STX16	5	SNARE complex; integral to membrane; SNAP receptor activity; protein binding; intracellular protein transport;
STX17	5	SNARE complex; integral to membrane; SNAP receptor activity; exocytosis; intracellular protein transport;
STX6	5	SNARE complex; integral to membrane; SNAP receptor activity; protein binding; intracellular protein transport;

Genes shared at least 2 KEGG pathways with STX3 (count: 0)

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Region: chr11:59522532..59573355 View in gBrowse