ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	STX16
Symbol Alias	hsyn16, SYN16
Approved Name	syntaxin 16
Location	20q13.32
Position	chr20:57226328-57254582, +
External Links	HGNC: 11431 Entrez Gene: 8675 Ensembl: ENSG00000124222 UCSC: uc002xzi.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component		243
GO:0005515	protein binding	Molecular Function	IPI[18195106]	910
GO:0005484	SNAP receptor activity	Molecular Function	IDA[15215310]	13
GO:0000139	Golgi membrane	Cellular Component		95
GO:0042147	retrograde transport, endosome to Golgi	Biological Process	IDA[15215310]	5
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0016021	integral to membrane	Cellular Component		845
GO:0031201	SNARE complex	Cellular Component	IDA[19620288]; TAS[15215310]	13
GO:0006886	intracellular protein transport	Biological Process		43
GO:0006891	intra-Golgi vesicle-mediated transport	Biological Process	TAS[9464276]	13
GO:0005737	cytoplasm	Cellular Component	TAS[9587053]	690
GO:0005794	Golgi apparatus	Cellular Component	TAS[9587053]	157

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04130	SNARE interactions in vesicular transport	20

Genes shared at least 5 GO terms with STX16 (count: 24)

Gene Symbol	Pathway Count	Pathway List
STX6	9	protein binding; SNAP receptor activity; Golgi membrane; retrograde transport, endosome to Golgi; integral to membrane; SNARE complex; intracellular protein transport; Golgi apparatus; Golgi vesicle transport;
STX5	8	nucleolus; SNAP receptor activity; Golgi membrane; retrograde transport, endosome to Golgi; integral to membrane; SNARE complex; intracellular protein transport; Golgi apparatus;
GOSR1	8	SNAP receptor activity; Golgi membrane; retrograde transport, endosome to Golgi; integral to membrane; SNARE complex; intra-Golgi vesicle-mediated transport; Golgi apparatus; Golgi vesicle transport;
COG3	7	nucleolus; protein binding; intracellular protein transport; intra-Golgi vesicle-mediated transport; cytoplasm; Golgi apparatus; Golgi vesicle transport;
YKT6	7	SNAP receptor activity; Golgi membrane; retrograde transport, endosome to Golgi; SNARE complex; cytoplasm; Golgi apparatus; Golgi vesicle transport;
SCAMP2	6	nucleolus; protein binding; intracellular membrane-bounded organelle; integral to membrane; Golgi apparatus; Golgi vesicle transport;
STX18	6	protein binding; SNAP receptor activity; Golgi membrane; integral to membrane; intracellular protein transport; Golgi vesicle transport;
AP3B2	5	nucleolus; intracellular protein transport; cytoplasm; Golgi apparatus; Golgi vesicle transport;
COG5	5	nucleolus; protein binding; Golgi membrane; intra-Golgi vesicle-mediated transport; Golgi apparatus;
STAP1	5	nucleolus; protein binding; intracellular membrane-bounded organelle; intracellular protein transport; cytoplasm;
TFAP2A	5	nucleolus; protein binding; intracellular membrane-bounded organelle; cytoplasm; Golgi apparatus;
COG2	5	protein binding; Golgi membrane; intracellular protein transport; intra-Golgi vesicle-mediated transport; Golgi vesicle transport;
COG7	5	protein binding; Golgi membrane; intracellular protein transport; Golgi apparatus; Golgi vesicle transport;
COPB1	5	protein binding; Golgi membrane; intracellular protein transport; intra-Golgi vesicle-mediated transport; Golgi vesicle transport;
GABARAPL2	5	protein binding; Golgi membrane; intra-Golgi vesicle-mediated transport; cytoplasm; Golgi apparatus;
STX1A	5	protein binding; SNAP receptor activity; integral to membrane; SNARE complex; intracellular protein transport;
STX3	5	protein binding; SNAP receptor activity; integral to membrane; SNARE complex; intracellular protein transport;
STX4	5	protein binding; SNAP receptor activity; integral to membrane; SNARE complex; intracellular protein transport;
TMED10	5	protein binding; integral to membrane; intracellular protein transport; Golgi apparatus; Golgi vesicle transport;
TMED2	5	protein binding; intracellular membrane-bounded organelle; integral to membrane; intracellular protein transport; Golgi apparatus;
YIF1A	5	protein binding; Golgi membrane; intracellular membrane-bounded organelle; integral to membrane; Golgi apparatus;
STX7	5	SNAP receptor activity; integral to membrane; SNARE complex; intracellular protein transport; Golgi vesicle transport;
PARM1	5	Golgi membrane; intracellular membrane-bounded organelle; integral to membrane; cytoplasm; Golgi apparatus;
COPB2	5	intracellular protein transport; intra-Golgi vesicle-mediated transport; cytoplasm; Golgi apparatus; Golgi vesicle transport;

Genes shared at least 2 KEGG pathways with STX16 (count: 0)

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Region: chr20:57226328..57254582 View in gBrowse