ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol SYT1
Previous Symbol SYT, SVP65
Symbol Alias P65
Approved Name synaptotagmin I
Location 12q21.2
Position chr12:79257773-79845788, 1
External Links HGNC: 11509
Entrez Gene: 6857
Ensembl: ENSG00000067715
UCSC: uc001syv.3
No. of Studies 4 (significant: 2; non-significant: 2; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 4)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Brookes KJ, 2005 (b) no SNP showed evidence of association Non-significant
Brookes K, 2006 UNPHASED TDT P-value=0.0674, global P-value=0.681, WHAP TDT P_sum P-value=0.271, no SNP with nominal P-value<0.05 located in this gene Non-significant
Sanchez-Mora, C., 2012 nominal differences were found with both adulthood ADHD and children ADHD. Significant
Guan L, 2009 2 SNPs in this gene achieved significance for ADHD-I and ADHD-C respectively in single SNP association analysis. Significant

Gene related SNPs (count: 64)

Literature-origin SNPs (count: 5)

LD-proxies (count: 59)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 35)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 35)


Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SYT1 (count: 28)

Genes shared at least 2 KEGG pathways with SYT1 (count: 0)

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Region: chr12:79257773..79845788 View in gBrowse
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