ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs1245769 dbSNP Ensembl
Location	Chr12:79776101(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000261205; ENST00000457153; ENST00000393240; ENST00000549527; ENST00000552744) nc_transcript_variant(ENST00000549527)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes KJ, 2005 (b)			MRM P-value=0.09, Case-control P-value=0.23, TDT P-value=0.7...... MRM P-value=0.09, Case-control P-value=0.23, TDT P-value=0.73 More...	was not significant in both TDT analysis and case-control an...... was not significant in both TDT analysis and case-control analysis More...	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SYT1	synaptotagmin I	12cen-q21	4(2/2/0)

Genes from other sources (count: 0)

SNPs in LD with rs1245769 (count: 17) View in gBrowse (chr12:79760388..79802302 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 17)

rs_ID	Functional Annotation	r²[population]
rs7966962	intron_variant; nc_transcript_variant	0.922[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.976[GIH]; 1.0[JPT]; 0.902[LWK]; 0.948[MEX]; 0.953[MKK]; 1.0[TSI]; 0.806[YRI]
rs2895728	intron_variant; nc_transcript_variant	0.826[CEU]; 0.889[TSI]
rs1245767	intron_variant; nc_transcript_variant	0.851[CEU]
rs10778657	downstream_gene_variant; intron_variant; nc_transcript_variant	0.88[CEU]
rs12371960	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.902[CHD]; 0.948[GIH]; 1.0[JPT]; 0.964[LWK]; 0.953[MKK]; 1.0[TSI]; 1.0[YRI]
rs1245765	intron_variant; nc_transcript_variant	1.0[CEU]; 0.977[TSI]
rs1245778	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs10861941	intron_variant; nc_transcript_variant	0.849[TSI]
rs2400395	intron_variant; nc_transcript_variant	0.922[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 0.976[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.953[MKK]; 1.0[TSI]; 0.864[YRI]
rs9788036	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.938[JPT]; 1.0[YRI]
rs1465044	intron_variant; nc_transcript_variant	0.864[CEU]
rs1245766	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.966[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs7308297	intron_variant; nc_transcript_variant	0.921[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.901[LWK]; 0.948[MEX]; 0.953[MKK]; 0.977[TSI]; 0.806[YRI]
rs10861975	intron_variant; nc_transcript_variant	0.914[CEU]; 0.954[TSI]
rs1465051	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs10861976	intron_variant; nc_transcript_variant	0.911[CEU]; 0.977[TSI]
rs1245770	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.975[CHD]; 0.976[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]