ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs7315638 dbSNP Ensembl
Location	Chr12:79807279(Fwd)
Variant Alleles	T/C
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000457153; ENST00000261205; ENST00000393240; ENST00000549527; ENST00000552744; ENST00000550268; ENST00000553165) nc_transcript_variant(ENST00000549527; ENST00000550268; ENST00000553165)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.044, Empi...... single SNP association analyses: Nominal P-value=0.044, Empirical P-value=0.299 for ADHD-I More...	non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More...	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SYT1	synaptotagmin I	12cen-q21	4(2/2/0)

Genes from other sources (count: 0)

SNPs in LD with rs7315638 (count: 34) View in gBrowse (chr12:79760767..79922319 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 1)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs10861968	downstream_gene_variant; intron_variant; nc_transcript_variant	1(1/0/0)	0.918[CEU]

LD-proxies (count: 33)

rs_ID	Functional Annotation	r²[population]
rs1465046	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.955[MKK]; 0.967[TSI]
rs7303658	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs1465049	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.949[JPT]
rs4609662	intron_variant; nc_transcript_variant	0.917[CEU]
rs1465045	intron_variant; nc_transcript_variant	0.835[CHB]; 0.899[JPT]
rs17005561	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.934[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.955[MKK]; 0.967[TSI]
rs1405495	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.95[JPT]
rs17005588	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]
rs7138252	upstream_gene_variant	0.819[CHB]; 0.901[JPT]; 0.865[MEX]
rs12581451	intron_variant; nc_transcript_variant	1.0[CEU]; 0.835[CHB]; 0.899[JPT]
rs2701566	intron_variant; nc_transcript_variant	0.841[CEU]; 0.905[GIH]; 0.908[TSI]
rs17041667	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.849[GIH]; 1.0[JPT]; 0.904[LWK]; 1.0[MEX]; 0.846[MKK]; 0.968[TSI]
rs11608780	intron_variant; nc_transcript_variant	0.898[CEU]; 0.894[CHB]; 1.0[JPT]
rs4578461	intron_variant; nc_transcript_variant	1.0[CEU]; 0.821[CHB]; 0.87[JPT]
rs1405493	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 0.94[CHB]; 0.884[CHD]; 1.0[GIH]; 0.95[JPT]; 0.878[MEX]; 0.869[MKK]; 1.0[TSI]
rs11612225	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs17005546	intron_variant; nc_transcript_variant	1.0[CEU]; 0.833[CHB]; 0.892[JPT]
rs1245774	intron_variant; nc_transcript_variant	0.869[CHB]
rs11608808	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs7295888	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.955[MKK]; 1.0[TSI]
rs7133421	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12423434	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs10778675		0.819[CHB]; 0.901[JPT]; 0.865[MEX]
rs12579420	intron_variant; nc_transcript_variant	0.898[CEU]
rs1465047	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs1526955	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs7971881	feature_truncation; intron_variant; nc_transcript_variant	0.819[CEU]
rs10506815	intron_variant; nc_transcript_variant	1.0[CEU]; 0.835[CHB]; 0.899[JPT]
rs1405497	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.935[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.955[MKK]; 0.967[TSI]
rs17005544	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.835[CHB]; 0.905[GIH]; 0.899[JPT]; 0.878[MEX]; 0.967[TSI]
rs1358243	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs4842313	intron_variant; nc_transcript_variant; upstream_gene_variant	0.841[CEU]; 0.819[CHB]; 0.901[JPT]
rs1465048	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]