ADHDgene Database

SNP Report

Basic Info

Name	rs2251214 dbSNP Ensembl
Location	Chr12:79823851(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000393240; ENST00000261205; ENST00000457153; ENST00000552744; ENST00000549527; ENST00000553165; ENST00000550268) nc_transcript_variant(ENST00000549527; ENST00000553165; ENST00000550268)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Sanchez-Mora, C., 2012			P-value=0.116, Genotype12+22 vs11: P-value=0.114, OR(95%CI)=...... P-value=0.116, Genotype12+22 vs11: P-value=0.114, OR(95%CI)=1.19(0.96¨C1.49); Genotypes22 vs11+12: P-value=0.077, OR(95%CI)=1.52(0.94¨C2.38); allelic P-value=0,044, OR(95%CI)=1.20(1¨C1.45) More...	"When adults with ADHD were considered, nominal differences ...... "When adults with ADHD were considered, nominal differences were found for nine SNPs located in five genes. " More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SYT1	synaptotagmin I	12cen-q21	4(2/2/0)

SNPs in LD with rs2251214 (count: 1) View in gBrowse (chr12:79811286..79823851 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.