ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DTNA
Symbol Alias	D18S892E, DTN, DTN-1, DTN-2, DTN-3, DRP3
Approved Name	dystrobrevin, alpha
Name Alias	dystrophin-related protein 3
Location	18q12
Position	chr18:32073254-32471808, +
External Links	HGNC: 3057 Entrez Gene: 1837 Ensembl: ENSG00000134769 UCSC: uc010dmn.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030054	cell junction	Cellular Component		77
GO:0043234	protein complex	Cellular Component	IDA[18468998]	45
GO:0007274	neuromuscular synaptic transmission	Biological Process	TAS[9119373]	5
GO:0008270	zinc ion binding	Molecular Function		323
GO:0007165	signal transduction	Biological Process	TAS[10767327]	171
GO:0007268	synaptic transmission	Biological Process	TAS[8845841]	96
GO:0005886	plasma membrane	Cellular Component		772
GO:0006941	striated muscle contraction	Biological Process	TAS[10767327]	4
GO:0005515	protein binding	Molecular Function	IPI[19931615]	910
GO:0045202	synapse	Cellular Component		31
GO:0005737	cytoplasm	Cellular Component		690
GO:0005509	calcium ion binding	Molecular Function		124

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DTNA (count: 19)

Gene Symbol	Pathway Count	Pathway List
SNAP25	6	cell junction; synaptic transmission; plasma membrane; protein binding; synapse; cytoplasm;
SNCA	6	cell junction; zinc ion binding; plasma membrane; protein binding; cytoplasm; calcium ion binding;
PRKCB	6	zinc ion binding; signal transduction; synaptic transmission; plasma membrane; protein binding; cytoplasm;
ACHE	5	cell junction; synaptic transmission; plasma membrane; protein binding; synapse;
GOPC	5	cell junction; protein complex; plasma membrane; protein binding; cytoplasm;
GRIN2A	5	cell junction; zinc ion binding; synaptic transmission; plasma membrane; protein binding;
GRIN2B	5	cell junction; zinc ion binding; synaptic transmission; plasma membrane; protein binding;
RAPSN	5	cell junction; zinc ion binding; synaptic transmission; plasma membrane; cytoplasm;
RASGRP2	5	cell junction; signal transduction; plasma membrane; synapse; calcium ion binding;
SYT1	5	cell junction; synaptic transmission; plasma membrane; protein binding; calcium ion binding;
SYT2	5	cell junction; synaptic transmission; plasma membrane; protein binding; calcium ion binding;
MAPK1	5	protein complex; signal transduction; synaptic transmission; protein binding; cytoplasm;
ADAM8	5	zinc ion binding; plasma membrane; protein binding; cytoplasm; calcium ion binding;
CBL	5	zinc ion binding; plasma membrane; protein binding; cytoplasm; calcium ion binding;
LPXN	5	zinc ion binding; signal transduction; plasma membrane; protein binding; cytoplasm;
ADCY4	5	signal transduction; synaptic transmission; plasma membrane; protein binding; cytoplasm;
ADRA2A	5	signal transduction; plasma membrane; protein binding; synapse; cytoplasm;
APBB1	5	signal transduction; plasma membrane; protein binding; synapse; cytoplasm;
KCNIP1	5	signal transduction; synaptic transmission; plasma membrane; protein binding; calcium ion binding;

Genes shared at least 2 KEGG pathways with DTNA (count: 0)

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Region: chr18:32073254..32471808 View in gBrowse