ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045202
Name synapse
Type cellular component
No. of Genes in ADHDgene  35
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 35)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) IEA
CADM2 cell adhesion molecule 2 3p12.2 1(1/0/0) IEA
CPLX4 complexin 4 18q21.32 1(1/0/0) IEA
DACT1 dishevelled-binding antagonist of beta-catenin 1 14q22.3 1(0/1/0) IEA
MAP1B microtubule-associated protein 1B 5q13 1(0/0/1) IEA
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1) ISS
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) IEA
CPLX1 complexin 1 4p16.3 1(1/0/0) IEA
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) ISS
CPLX2 complexin 2 5q35.2 2(1/0/1) IEA

Genes from other sources Help (count: 25)

Approved Symbol Approved Name Source Evidence[PMID]
CABP4 calcium binding protein 4 Mapped by significant region TAS[16960802]
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IDA[17658481]
DTNA dystrobrevin, alpha Mapped by significant region IEA
UBE2I ubiquitin-conjugating enzyme E2I Mapped by significant region IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IDA[8460160]
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 Mapped by significant region IEA
MGLL monoglyceride lipase Mapped by PBA pathway IEA
CYFIP2 cytoplasmic FMR1 interacting protein 2 Mapped by significant region IDA[11438699]
PRRT2 proline-rich transmembrane protein 2 Mapped by CNV IEA
CYFIP1 cytoplasmic FMR1 interacting protein 1 Mapped by significant region IEA
EGFLAM EGF-like, fibronectin type III and laminin G domains Mapped by significant region IEA
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IDA[12843239]
CDH2 cadherin 2, type 1, N-cadherin (neuronal) Mapped by significant region IEA
CACNB4 calcium channel, voltage-dependent, beta 4 subunit Mapped by PBA pathway IDA[16525042]
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP ISS
FRRS1L ferric-chelate reductase 1-like Mapped by significant region IEA
TRAPPC4 trafficking protein particle complex 4 Mapped by significant region ISS[11018053]
SHISA9 shisa family member 9 Mapped by significant region ISS
CBLN3 cerebellin 3 precursor Mapped by significant region IEA
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region IEA
MYO7A myosin VIIA Mapped by significant region IDA[8842737]
NLGN1 neuroligin 1 Mapped by CNV IBA; ISS
SNAP23 synaptosomal-associated protein, 23kDa Mapped by PBA pathway IEA
SNAP29 synaptosomal-associated protein, 29kDa Mapped by CNV IEA
MAP1S microtubule-associated protein 1S Mapped by PBA pathway IDA[17658481]