ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CPLX4
Symbol Alias	CPX-IV
Approved Name	complexin 4
Location	18q21.32
Position	chr18:56962634-56985881, -
External Links	HGNC: 24330 Entrez Gene: 339302 Ensembl: ENSG00000166569 UCSC: uc002lhy.2
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Sanchez-Mora, C., 2012	nominal differences were found with adulthood ADHD.	Significant

Gene related SNPs (count: 23)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs9973180	Chr18:56954214(Fwd)	intron_variant	2(0/2/0)
rs10503024	Chr18:56975671(Fwd)	intron_variant	1(1/0/0)
rs640401	Chr18:56966832(Fwd)	intron_variant	1(1/0/0)

rs_ID	Location	Functional Annotation
rs9319946	Chr18:56952229(Fwd)	intron_variant
rs17696441	Chr18:56948020(Fwd)	intron_variant
rs17696454	Chr18:56953499(Fwd)	intron_variant
rs9948612	Chr18:56952800(Fwd)	intron_variant
rs9965777	Chr18:56945392(Fwd)	intron_variant; upstream_gene_variant
rs9960456	Chr18:56947481(Fwd)	intron_variant
rs17769086	Chr18:56945838(Fwd)	intron_variant; upstream_gene_variant
rs12232751	Chr18:56966260(Fwd)	intron_variant
rs508858	Chr18:56968427(Fwd)	intron_variant
rs7228681	Chr18:56964270(Fwd)	intron_variant
rs536113	Chr18:56967796(Fwd)	intron_variant
rs599535	Chr18:56977515(Fwd)	intron_variant
rs537048	Chr18:56967701(Fwd)	intron_variant
rs11662475	Chr18:56969154(Fwd)	intron_variant
rs4940455	Chr18:56961641(Fwd)	downstream_gene_variant; intron_variant
rs9973070	Chr18:56954004(Fwd)	intron_variant
rs7243416	Chr18:56963272(Fwd)	3_prime_UTR_variant; intron_variant
rs10871768	Chr18:56963119(Fwd)	3_prime_UTR_variant; intron_variant
rs1980176	Chr18:56987447(Fwd)	upstream_gene_variant
rs4108696	Chr18:56980847(Fwd)	intron_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q21.31-21.32	chr18:53800000-59000000	1 (1/0/0)

Gene related GO terms (count: 7)

ID	Name	Type	No. of Genes in ADHDgene
GO:0006836	neurotransmitter transport	Biological Process	5
GO:0016020	membrane	Cellular Component	139
GO:0006887	exocytosis	Biological Process	14
GO:0030054	cell junction	Cellular Component	77
GO:0019905	syntaxin binding	Molecular Function	6
GO:0046928	regulation of neurotransmitter secretion	Biological Process	5
GO:0045202	synapse	Cellular Component	31

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CPLX4 (count: 0)

Genes shared at least 2 KEGG pathways with CPLX4 (count: 0)

View in gBrowse

Region: chr18:56962634..56985881 View in gBrowse