ADHDgene Database

Gene Report

Basic Info

Approved Symbol	MAP1B
Symbol Alias	MAP5
Approved Name	microtubule-associated protein 1B
Location	5q13
Position	chr5:71403061-71505397, +
External Links	HGNC: 6836 Entrez Gene: 4131 Ensembl: ENSG00000131711 UCSC: uc003kbw.3
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lesch KP, 2008	Trend associated SNP was mapped in this gene.	Trend

Gene related SNPs (count: 11)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs2199161	Chr5:71410356(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs1979309	Chr5:71407544(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs1979310	Chr5:71407658(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs1979311	Chr5:71407890(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs1531310	Chr5:71411004(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs2337390	Chr5:71408867(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs1459217	Chr5:71414800(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant
rs1531312	Chr5:71411718(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant
rs6453442	Chr5:71413319(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant
rs1466345	Chr5:71414166(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant
rs1459216	Chr5:71414659(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0009987	cellular process	Biological Process	IDA[19567321]	1
GO:0005886	plasma membrane	Cellular Component	IDA[19567321]	772
GO:0030054	cell junction	Cellular Component		77
GO:0016358	dendrite development	Biological Process		9
GO:0043197	dendritic spine	Cellular Component		12
GO:0032387	negative regulation of intracellular transport	Biological Process		3
GO:0045773	positive regulation of axon extension	Biological Process		7
GO:0045202	synapse	Cellular Component		31
GO:0061162	establishment of monopolar cell polarity	Biological Process		1
GO:0047497	mitochondrion transport along microtubule	Biological Process		4
GO:0005874	microtubule	Cellular Component		52
GO:0005875	microtubule associated complex	Cellular Component		13
GO:0005515	protein binding	Molecular Function	IPI[12147674]	910
GO:0005829	cytosol	Cellular Component		447
GO:0001578	microtubule bundle formation	Biological Process		8
GO:0005198	structural molecule activity	Molecular Function	NAS[1881920]	29

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MAP1B (count: 5)

Gene Symbol	Pathway Count	Pathway List
MAPT	8	plasma membrane; negative regulation of intracellular transport; positive regulation of axon extension; mitochondrion transport along microtubule; microtubule; microtubule associated complex; protein binding; cytosol;
MAP1S	7	synapse; mitochondrion transport along microtubule; microtubule; microtubule associated complex; protein binding; cytosol; microtubule bundle formation;
BAIAP2	5	plasma membrane; cell junction; dendrite development; protein binding; cytosol;
CDK5RAP2	5	cell junction; microtubule; protein binding; cytosol; microtubule bundle formation;
MAP1A	5	microtubule; microtubule associated complex; protein binding; cytosol; structural molecule activity;

Genes shared at least 2 KEGG pathways with MAP1B (count: 0)

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Region: chr5:71403061..71505397 View in gBrowse