ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NMNAT2
Previous Symbol	C1orf15
Symbol Alias	KIAA0479, PNAT2
Approved Name	nicotinamide nucleotide adenylyltransferase 2
Previous Name	chromosome 1 open reading frame 15
Location	1q25
Position	chr1:183217372-183387737, -
External Links	HGNC: 16789 Entrez Gene: 23057 Ensembl: ENSG00000157064 UCSC: uc001gqc.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
1q25.3	chr1:180300000-185800000	1 (1/0/0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045202	synapse	Cellular Component		31
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0019674	NAD metabolic process	Biological Process		5
GO:0000139	Golgi membrane	Cellular Component		95
GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	Molecular Function		2
GO:0004515	nicotinate-nucleotide adenylyltransferase activity	Molecular Function	IDA[16118205]	2
GO:0005524	ATP binding	Molecular Function		228
GO:0005802	trans-Golgi network	Cellular Component		28
GO:0006766	vitamin metabolic process	Biological Process		13
GO:0006767	water-soluble vitamin metabolic process	Biological Process		13
GO:0009435	NAD biosynthetic process	Biological Process	IC[16118205]	6
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0005770	late endosome	Cellular Component		14
GO:0005794	Golgi apparatus	Cellular Component	IDA[16118205]	157

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00760	Nicotinate and nicotinamide metabolism	9

Genes shared at least 5 GO terms with NMNAT2 (count: 8)

Gene Symbol	Pathway Count	Pathway List
NAPRT1	8	small molecule metabolic process; NAD metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; NAD biosynthetic process; nucleus; cytoplasm; Golgi apparatus;
NMNAT3	8	small molecule metabolic process; NAD metabolic process; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; ATP binding; vitamin metabolic process; water-soluble vitamin metabolic process; NAD biosynthetic process;
NADSYN1	6	small molecule metabolic process; NAD metabolic process; ATP binding; vitamin metabolic process; water-soluble vitamin metabolic process; NAD biosynthetic process;
PRKD1	6	small molecule metabolic process; ATP binding; trans-Golgi network; nucleus; cytoplasm; Golgi apparatus;
QPRT	5	small molecule metabolic process; NAD metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; NAD biosynthetic process;
SHMT1	5	small molecule metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; nucleus; cytoplasm;
PARM1	5	Golgi membrane; nucleus; cytoplasm; late endosome; Golgi apparatus;
MAPK1	5	ATP binding; nucleus; cytoplasm; late endosome; Golgi apparatus;

Genes shared at least 2 KEGG pathways with NMNAT2 (count: 8)

Gene Symbol	Pathway Count	Pathway List
ENPP1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
ENPP3	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NADSYN1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NAPRT1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NMNAT3	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NNMT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NT5M	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
QPRT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;

View in gBrowse

Region: chr1:183217372..183387737 View in gBrowse