ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol SYP
Symbol Alias MRX96
Approved Name synaptophysin
Location Xp11.23-p11.22
Position chrX:49044269-49056718, -1
External Links HGNC: 11506
Entrez Gene: 6855
Ensembl: ENSG00000102003
UCSC: uc004dmz.1
No. of Studies 4 (significant: 4; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 4)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Guan L, 2009 1 SNP in this gene achieved significance for ADHD-I in single SNP association analysis. Significant
Liu, L.,2013 After re?ning the phenotype into gender and symptomatic subtypes, signi?cant associations between SYP and ADHD were observed, particularly for the ADHD-I subtype. Significant
Brookes K, 2006 UNPHASED TDT P-value=0.045, global P-value=0.038; OR=1.25, one or more SNPs with nominal P-value<0.05 located in this gene Significant
Brookes KJ, 2005 (b) 1 SNP remained significant following case-control and TDT analysis of the individually genotyped data Significant

Gene related SNPs (count: 4)

Literature-origin SNPs (count: 3)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 21)

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SYP (count: 1)

Genes shared at least 2 KEGG pathways with SYP (count: 0)

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Region: chrX:49044269..49056718 View in gBrowse
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