ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04730
Name Long-term depression
No. of Genes in ADHDgene  27
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 27)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
PRKG1 protein kinase, cGMP-dependent, type I 10q11.2 2(0/1/1)
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0)
GRM5 glutamate receptor, metabotropic 5 11q14.3 2(1/0/1)
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0)
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 4p16.1 1(1/0/0)
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0)

Genes from other sources Help(count: 19)

Approved Symbol Approved Name Location Source
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
PLA2G10 phospholipase A2, group X 16p13.1-p12 Mapped by significant region; Mapped by PBA pathway
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1p35 Mapped by PBA pathway
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 22q13.1 Mapped by PBA pathway
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 3p26.1 Mapped by CNV
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 11q21-q22 Mapped by significant region
PLA2G4B phospholipase A2, group IVB (cytosolic) 15q11.2-q21.3 Mapped by PBA pathway
PLA2G2E phospholipase A2, group IIE 1p36.13 Mapped by PBA pathway
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 11q13 Mapped by significant region
PLA2G3 phospholipase A2, group III 22q12.2 Mapped by PBA pathway
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 19p13 Mapped by PBA pathway
RYR1 ryanodine receptor 1 (skeletal) 19q13.1 Mapped by PBA pathway
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 12p11.23 Mapped by Literature SNP
PLA2G2D phospholipase A2, group IID 1p36.12 Mapped by PBA pathway
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
PLA2G5 phospholipase A2, group V 1p36-p34 Mapped by PBA pathway
PLCB2 phospholipase C, beta 2 15q15.1 Mapped by PBA pathway
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 11q23.1 Mapped by significant region
PLA2G1B phospholipase A2, group IB (pancreas) 12q24.31 Mapped by PBA pathway