ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005768
Name endosome
Type cellular component
No. of Genes in ADHDgene  29
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 29)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRA2C adrenoceptor alpha 2C 4p16.3 7(2/4/1) TAS[10196213]
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS[2668275]
ADRB2 adrenoceptor beta 2, surface 5q31-q32 2(1/1/0) TAS[10734107]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) TAS
DGKH diacylglycerol kinase, eta 13q13.3 2(1/1/0) IDA[12810723]
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5q31-q33 1(1/0/0) IEA

Genes from other sources Help (count: 23)

Approved Symbol Approved Name Source Evidence[PMID]
BIRC6 baculoviral IAP repeat containing 6 Mapped by CNV IDA[18329369]
CLVS2 clavesin 2 Mapped by significant region IDA[19651769]
CCDC115 coiled-coil domain containing 115 Mapped by significant region IEA
GAPVD1 GTPase activating protein and VPS9 domains 1 Mapped by significant region IEA
TLR9 toll-like receptor 9 Mapped by LD-proxy ISS
BDKRB2 bradykinin receptor B2 Mapped by PBA pathway IDA[17077303]
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway IDA; TAS[10913182]
GOLPH3 golgi phosphoprotein 3 (coat-protein) Mapped by significant region IEA
PLD1 phospholipase D1, phosphatidylcholine-specific Mapped by PBA pathway IDA[14718562]
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) Mapped by PBA pathway IDA[15215310]
KIAA0196 KIAA0196 Mapped by CNV IEA
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) Mapped by significant region IDA
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase Mapped by significant region IDA
RABEPK Rab9 effector protein with kelch motifs Mapped by significant region TAS[9230071]
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 Mapped by significant region; Mapped by PBA pathway IEA
SORT1 sortilin 1 Mapped by CNV NAS
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway IDA[10679098]
RAB11FIP3 RAB11 family interacting protein 3 (class II) Mapped by significant region IDA[16148947]
UNC93B1 unc-93 homolog B1 (C. elegans) Mapped by significant region IDA; ISS
BACE1 beta-site APP-cleaving enzyme 1 Mapped by significant region IDA[10531052]
GIF gastric intrinsic factor (vitamin B synthesis) Mapped by significant region IDA[8886952]
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa Mapped by significant region IEA
EXPH5 exophilin 5 Mapped by CNV; Mapped by significant region IDA[19966785]