ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol SLC1A3
Symbol Alias EAAT1, GLAST, EA6
Approved Name solute carrier family 1 (glial high affinity glutamate transporter), member 3
Name Alias glutamate transporter variant EAAT1ex9skip
Location 5p13
Position chr5:36606457-36688436, +
External Links HGNC: 10941
Entrez Gene: 6507
Ensembl: ENSG00000079215
UCSC: uc003jkj.3
No. of Studies 2 (significant: 1; non-significant: 1; trend: 0)
Source Literature-origin; Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Turic D, 2005(a) two marker haplotype (rs3776581/rs2269272) TRANSMIT P-value=0.016, X2(df=3)=10.47; two marker haplotype (rs2269272/rs2032893) TRANSMIT P-value=0.013, X2(df=3)=11.60; Haplotype T/G of rs2269272/rs2032893 P-value=0.003, X2(df=1)=9.43; genetic variation in SLC1A3 may contribute to susceptibility to ADHD Significant
Laurin N, 2008(a) single marker and haplotype analyses yielded little evidence for significant association Non-significant

Gene related SNPs (count: 72)

Literature-origin SNPs (count: 23)

LD-proxies (count: 49)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Gene related GO terms (count: 29)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 29)

Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with SLC1A3 (count: 13)

Genes shared at least 2 KEGG pathways with SLC1A3 (count: 0)

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Region: chr5:36606457..36688436 View in gBrowse
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