ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLC7A10
Symbol Alias	asc-1
Approved Name	solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
Previous Name	solute carrier family 7, (cationic amino acid transporter, y+ system) member 10
Location	19q13.1
Position	chr19:33699570-33716756, -
External Links	HGNC: 11058 Entrez Gene: 56301 Ensembl: ENSG00000130876 UCSC: uc002num.2
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin; Mapped by CNV

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Elia, J., 2012	This gene was found directly affected by CNVRs overrepresented in individuals with ADHD.	Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2012]_9	chr19:38427720-38444834 (NCBI36 / hg18)	17115	19q13.11	Del	2:2:1(80%)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0015804	neutral amino acid transport	Biological Process	IDA[10863037]	3
GO:0015825	L-serine transport	Biological Process	TAS[10863037]	2
GO:0015175	neutral amino acid transmembrane transporter activity	Molecular Function	IDA[10863037]	4
GO:0015194	L-serine transmembrane transporter activity	Molecular Function	TAS[10863037]	2
GO:0006865	amino acid transport	Biological Process		5
GO:0007596	blood coagulation	Biological Process		83
GO:0005887	integral to plasma membrane	Cellular Component	NAS[10863037]	220
GO:0006811	ion transport	Biological Process		25
GO:0005886	plasma membrane	Cellular Component		772
GO:0055085	transmembrane transport	Biological Process		82
GO:0050900	leukocyte migration	Biological Process		13
GO:0042942	D-serine transport	Biological Process		1
GO:0042941	D-alanine transport	Biological Process		1
GO:0016020	membrane	Cellular Component	TAS[10734121]	139

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SLC7A10 (count: 4)

Gene Symbol	Pathway Count	Pathway List
SLC7A5	8	neutral amino acid transport; neutral amino acid transmembrane transporter activity; amino acid transport; blood coagulation; ion transport; plasma membrane; transmembrane transport; leukocyte migration;
SLC43A1	7	neutral amino acid transport; neutral amino acid transmembrane transporter activity; amino acid transport; integral to plasma membrane; ion transport; plasma membrane; transmembrane transport;
SLC3A2	7	neutral amino acid transmembrane transporter activity; amino acid transport; blood coagulation; ion transport; plasma membrane; transmembrane transport; leukocyte migration;
SLC4A3	5	integral to plasma membrane; ion transport; plasma membrane; transmembrane transport; membrane;

Genes shared at least 2 KEGG pathways with SLC7A10 (count: 0)

View in gBrowse

Region: chr19:33699570..33716756 View in gBrowse