ADHDgene Database

Gene Report

Basic Info

Approved Symbol	STMN1
Previous Symbol	LAP18, C1orf215
Symbol Alias	SMN, OP18, PR22, PP19, PP17, Lag, FLJ32206
Approved Name	stathmin 1
Previous Name	chromosome 1 open reading frame 215, "stathmin 1/oncoprotein 18"
Name Alias	oncoprotein 18
Location	1p36.11
Position	chr1:26210672-26233482, -
External Links	HGNC: 6510 Entrez Gene: 3925 Ensembl: ENSG00000117632 UCSC: uc010oev.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0009615	response to virus	Biological Process	IEP[16548883]	21
GO:0007409	axonogenesis	Biological Process		14
GO:0007165	signal transduction	Biological Process	NAS[8003023]	171
GO:0007052	mitotic spindle organization	Biological Process	IDA[9271428]	7
GO:0035556	intracellular signal transduction	Biological Process	TAS[2917975]	44
GO:0031115	negative regulation of microtubule polymerization	Biological Process		3
GO:0016020	membrane	Cellular Component		139
GO:0015631	tubulin binding	Molecular Function	IDA[10675326]	9
GO:0004871	signal transducer activity	Molecular Function	TAS[8003023]	49
GO:0007019	microtubule depolymerization	Biological Process	IDA[9880330]	2
GO:0005874	microtubule	Cellular Component		52
GO:0005829	cytosol	Cellular Component		447
GO:0005622	intracellular	Cellular Component		67
GO:0051272	positive regulation of cellular component movement	Biological Process		5

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04010	MAPK signaling pathway	69	The mitogen-activated protein kinase (MAPK) cascade is a hig...... The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli. More...

Genes shared at least 5 GO terms with STMN1 (count: 0)

Genes shared at least 2 KEGG pathways with STMN1 (count: 0)

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Region: chr1:26210672..26233482 View in gBrowse