ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CES1
Symbol Alias	HMSE, CES2, HMSE1, SES1, CEH, CES1A1, CES1A2
Approved Name	carboxylesterase 1
Previous Name	carboxylesterase 1 (monocyte/macrophage serine esterase 1)
Name Alias	human monocyte/macrophage serine esterase 1
Location	16q22.2
Position	chr16:55836763-55867075, -
External Links	HGNC: 1863 Entrez Gene: 1066 Ensembl: ENSG00000198848 UCSC: uc002eil.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004091	carboxylesterase activity	Molecular Function		40

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0080030	methyl indole-3-acetate esterase activity	Molecular Function		3
GO:0050253	retinyl-palmitate esterase activity	Molecular Function		9
GO:0080032	methyl jasmonate esterase activity	Molecular Function		3
GO:0080031	methyl salicylate esterase activity	Molecular Function		3
GO:0008152	metabolic process	Biological Process	TAS[1918003]	10
GO:0005788	endoplasmic reticulum lumen	Cellular Component		33
GO:0047374	methylumbelliferyl-acetate deacetylase activity	Molecular Function		2
GO:0009636	response to toxin	Biological Process	TAS[1918003]	15

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00983	Drug metabolism - other enzymes	25

Genes shared at least 5 GO terms with CES1 (count: 2)

Gene Symbol	Pathway Count	Pathway List
CES2	7	methyl indole-3-acetate esterase activity; retinyl-palmitate esterase activity; methyl jasmonate esterase activity; methyl salicylate esterase activity; endoplasmic reticulum lumen; methylumbelliferyl-acetate deacetylase activity; carboxylesterase activity;
CES5A	5	methyl indole-3-acetate esterase activity; retinyl-palmitate esterase activity; methyl jasmonate esterase activity; methyl salicylate esterase activity; carboxylesterase activity;

Genes shared at least 2 KEGG pathways with CES1 (count: 23)

Gene Symbol	Pathway Count	Pathway List
CES5A	2	Metabolic pathways; Drug metabolism - other enzymes;
ITPA	2	Metabolic pathways; Drug metabolism - other enzymes;
NAT2	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A1	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A10	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A3	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A4	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A5	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A6	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A7	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A8	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT1A9	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2A1	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2A2	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2A3	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B10	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B11	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B15	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B17	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B28	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B4	2	Metabolic pathways; Drug metabolism - other enzymes;
UGT2B7	2	Metabolic pathways; Drug metabolism - other enzymes;
UPB1	2	Metabolic pathways; Drug metabolism - other enzymes;

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Region: chr16:55836763..55867075 View in gBrowse