ADHDgene Database

Gene Report

Basic Info

Approved Symbol	HKDC1
Symbol Alias	FLJ37767, FLJ22761
Approved Name	hexokinase domain containing 1
Location	10q22.1
Position	chr10:70980059-71027315, 1
External Links	HGNC: 23302 Entrez Gene: 80201 Ensembl: ENSG00000156510 UCSC: uc001jpf.4
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	No significant or Trend associated SNP was mapped in this gene.	Non-significant

Gene related SNPs (count: 6)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs2394534	chr10:71029302(Fwd)	downstream_gene_variant; upstream_gene_variant	1(0/1/0)
rs906219	chr10:71026510(Fwd)	downstream_gene_variant; intron_variant; missense_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs5030948	chr10:71010375(Fwd)	downstream_gene_variant; synonymous_variant
rs10823325	chr10:71017444(Fwd)	intron_variant; upstream_gene_variant
rs10762271	chr10:71013216(Fwd)	downstream_gene_variant; intron_variant
rs1027793	chr10:71014413(Fwd)	intron_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005739	mitochondrion	cellular component	IDA	221
GO:0005524	ATP binding	molecular function	IEA	265
GO:0001678	cellular glucose homeostasis	biological process	IBA	2
GO:0004340	glucokinase activity	molecular function	IBA	2
GO:0008865	fructokinase activity	molecular function	IBA	2
GO:0005634	nucleus	cellular component	IDA	877
GO:0005730	nucleolus	cellular component	IDA	271
GO:0005829	cytosol	cellular component	IBA	485
GO:0006096	glycolysis	biological process	IBA	4
GO:0051156	glucose 6-phosphate metabolic process	biological process	IBA	2
GO:0019158	mannokinase activity	molecular function	IBA	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HKDC1 (count: 3)

Gene Symbol	Pathway Count	Pathway List
HK1	11	mitochondrion; ATP binding; cellular glucose homeostasis; glucokinase activity; fructokinase activity; nucleus; nucleolus; cytosol; glycolysis; glucose 6-phosphate metabolic process; mannokinase activity;
MAPK3	5	mitochondrion; ATP binding; nucleus; nucleolus; cytosol;
MAPK1	5	mitochondrion; ATP binding; nucleus; nucleolus; cytosol;

Genes shared at least 2 KEGG pathways with HKDC1 (count: 0)

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Region: chr10:70980059..71027315 View in gBrowse