ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TSTA3
Symbol Alias	FX, P35B, SDR4E1
Approved Name	tissue specific transplantation antigen P35B
Name Alias	short chain dehydrogenase/reductase family 4E, member 1, "GDP-L-fucose synthase"
Location	8q24.3
Position	chr8:144694788-144700218, -
External Links	HGNC: 12390 Entrez Gene: 7264 Ensembl: ENSG00000104522 UCSC: uc003yzb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation
rs2278898	Chr8:144691512(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	Cellular Component	IC[11698403]	690
GO:0007159	leukocyte cell-cell adhesion	Biological Process	NAS[11698403]	5
GO:0009055	electron carrier activity	Molecular Function	TAS[8910301]	18
GO:0016853	isomerase activity	Molecular Function		3
GO:0019673	GDP-mannose metabolic process	Biological Process	IDA[9525924]	2
GO:0019835	cytolysis	Biological Process		7
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	Biological Process	IDA[9525924]; TAS[11698403]	2
GO:0042356	GDP-4-dehydro-D-rhamnose reductase activity	Molecular Function	TAS[11698403]	1
GO:0050662	coenzyme binding	Molecular Function		3
GO:0050577	GDP-L-fucose synthase activity	Molecular Function	IDA[9525924]	1
GO:0000166	nucleotide binding	Molecular Function		73

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa01100	Metabolic pathways	237
hsa00051	Fructose and mannose metabolism	11
hsa00520	Amino sugar and nucleotide sugar metabolism	9

Genes shared at least 5 GO terms with TSTA3 (count: 0)

Genes shared at least 2 KEGG pathways with TSTA3 (count: 12)

Gene Symbol	Pathway Count	Pathway List
GMDS	3	Metabolic pathways; Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism;
GMPPA	3	Metabolic pathways; Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism;
HK1	3	Metabolic pathways; Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism;
HKDC1	3	Metabolic pathways; Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism;
ALDOA	2	Metabolic pathways; Fructose and mannose metabolism;
ALDOB	2	Metabolic pathways; Fructose and mannose metabolism;
FBP1	2	Metabolic pathways; Fructose and mannose metabolism;
FBP2	2	Metabolic pathways; Fructose and mannose metabolism;
GALT	2	Metabolic pathways; Amino sugar and nucleotide sugar metabolism;
GFPT2	2	Metabolic pathways; Amino sugar and nucleotide sugar metabolism;
NANS	2	Metabolic pathways; Amino sugar and nucleotide sugar metabolism;
SORD	2	Metabolic pathways; Fructose and mannose metabolism;

View in gBrowse

Region: chr8:144694788..144700218 View in gBrowse