ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GMDS
Symbol Alias	GMD, SDR3E1
Approved Name	GDP-mannose 4,6-dehydratase
Name Alias	"short chain dehydrogenase/reductase family 3E, member 1"
Location	6p25
Position	chr6:1624041-2245926, -1
External Links	HGNC: 4369 Entrez Gene: 2762 Ensembl: ENSG00000112699 UCSC: uc003mtq.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_71	chr6:2132467-2646249 (NCBI Build 35 (hg17))	513783	6p25.3-6p25.2	Deletion (hemizygous)	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0070401	NADP+ binding	molecular function	IDA[9525924]	1
GO:0008446	GDP-mannose 4,6-dehydratase activity	molecular function	IDA[9525924]; IGI[9603974]	1
GO:0005737	cytoplasm	cellular component	IC[9525924]	781
GO:0007219	Notch signaling pathway	biological process	ISS	23
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	biological process	IDA[9525924]; IEA	2
GO:0019673	GDP-mannose metabolic process	biological process	IDA[9525924]; IGI[9603974]	2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00051	Fructose and mannose metabolism	12

Genes shared at least 5 GO terms with GMDS (count: 0)

Genes shared at least 2 KEGG pathways with GMDS (count: 0)

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Region: chr6:1624041..2245926 View in gBrowse