ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04910
Name Insulin signaling pathway
No. of Genes in ADHDgene  29
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 29)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1)

Genes from other sources Help(count: 27)

Approved Symbol Approved Name Location Source
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 7q22.3 Mapped by CNV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 11q23.3 Mapped by significant region
PYGM phosphorylase, glycogen, muscle 11q12-q13.2 Mapped by significant region
SOCS1 suppressor of cytokine signaling 1 16p13.13 Mapped by significant region
SREBF1 sterol regulatory element binding transcription factor 1 17p11.2 Mapped by significant region
ACACA acetyl-CoA carboxylase alpha 17q21 Mapped by CNV
FBP2 fructose-1,6-bisphosphatase 2 9q22.3 Mapped by significant region
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 11q13.1 Mapped by significant region
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 9q22.1 Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1q21.2 Mapped by CNV
TSC1 tuberous sclerosis 1 9q34 Mapped by PBA pathway
MAPK9 mitogen-activated protein kinase 9 5q35 Mapped by CNV
PHKG2 phosphorylase kinase, gamma 2 (testis) 16p11.2 Mapped by CNV
PDPK1 3-phosphoinositide dependent protein kinase-1 16p13.3 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
TSC2 tuberous sclerosis 2 16p13.3 Mapped by significant region
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 5p13.1 Mapped by significant region
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 22q11.21 Mapped by CNV
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 2q35 Mapped by significant region
BAD BCL2-associated agonist of cell death 11q13.1 Mapped by significant region
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
LIPE lipase, hormone-sensitive 19q13.1-q13.2 Mapped by PBA pathway
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 11q13 Mapped by significant region
FBP1 fructose-1,6-bisphosphatase 1 9q22.3 Mapped by significant region
INS insulin 11p15.5 Mapped by Literature SNP