ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PRKAG3
Approved Name	protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Location	2q35
Position	chr2:219687106-219696809, -1
External Links	HGNC: 9387 Entrez Gene: 53632 Ensembl: ENSG00000115592 UCSC: uc002vjb.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005524	ATP binding	molecular function	IEA	265
GO:0007243	intracellular protein kinase cascade	biological process	TAS[10698692]	19
GO:0031588	AMP-activated protein kinase complex	cellular component	IEA	4
GO:0019901	protein kinase binding	molecular function	IDA[10698692]	59
GO:0005829	cytosol	cellular component	TAS	485
GO:0006633	fatty acid biosynthetic process	biological process	IEA	16
GO:0004679	AMP-activated protein kinase activity	molecular function	TAS[10698692]	3
GO:0015758	glucose transport	biological process	IEA	14
GO:0008286	insulin receptor signaling pathway	biological process	TAS	37
GO:0005978	glycogen biosynthetic process	biological process	IEA	2
GO:0046320	regulation of fatty acid oxidation	biological process	TAS	6
GO:0007050	cell cycle arrest	biological process	TAS	28

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04910	Insulin signaling pathway	29
hsa04920	Adipocytokine signaling pathway	9

Genes shared at least 5 GO terms with PRKAG3 (count: 4)

Gene Symbol	Pathway Count	Pathway List
PRKAG2	9	ATP binding; intracellular protein kinase cascade; AMP-activated protein kinase complex; protein kinase binding; cytosol; fatty acid biosynthetic process; insulin receptor signaling pathway; regulation of fatty acid oxidation; cell cycle arrest;
PRKAA1	8	ATP binding; AMP-activated protein kinase complex; cytosol; fatty acid biosynthetic process; AMP-activated protein kinase activity; insulin receptor signaling pathway; regulation of fatty acid oxidation; cell cycle arrest;
PRKAB2	7	AMP-activated protein kinase complex; cytosol; fatty acid biosynthetic process; AMP-activated protein kinase activity; insulin receptor signaling pathway; regulation of fatty acid oxidation; cell cycle arrest;
STK11	5	ATP binding; cytosol; insulin receptor signaling pathway; regulation of fatty acid oxidation; cell cycle arrest;

Genes shared at least 2 KEGG pathways with PRKAG3 (count: 4)

Gene Symbol	Pathway Count	Pathway List
PRKAA1	2	Insulin signaling pathway; Adipocytokine signaling pathway;
PRKAB2	2	Insulin signaling pathway; Adipocytokine signaling pathway;
MAPK9	2	Insulin signaling pathway; Adipocytokine signaling pathway;
PRKAG2	2	Insulin signaling pathway; Adipocytokine signaling pathway;

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Region: chr2:219687106..219696809 View in gBrowse