ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	GSTT1
Approved Name	glutathione S-transferase theta 1
Location	22q11.23
Position	chr22:24376133-24384680, -1
External Links	HGNC: 4641 Entrez Gene: 2952 Ensembl: ENSG00000184674 UCSC: uc002zze.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_37	chr22:22020325-23326630 (NCBI Build 36.1 (hg18))	1306306	22q11.23	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005829	cytosol	cellular component	IDA[8799324]	485
GO:0042493	response to drug	biological process	IEA	73
GO:0006749	glutathione metabolic process	biological process	IDA	7
GO:0004602	glutathione peroxidase activity	molecular function	IDA[9307035]	5
GO:0014070	response to organic cyclic compound	biological process	IEA	7
GO:0004364	glutathione transferase activity	molecular function	IDA	5

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa00982	Drug metabolism - cytochrome P450	27
hsa00980	Metabolism of xenobiotics by cytochrome P450	24
hsa00480	Glutathione metabolism	8

Genes shared at least 5 GO terms with GSTT1 (count: 0)

Genes shared at least 2 KEGG pathways with GSTT1 (count: 23)

Gene Symbol	Pathway Count	Pathway List
GSTP1	3	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450; Glutathione metabolism;
GSTT2	3	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450; Glutathione metabolism;
UGT2B10	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B7	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
CYP2E1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A4	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B28	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A3	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B15	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2A3	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A7	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A10	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3A1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A5	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A8	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B4	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B17	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3B2	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A9	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A6	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B11	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3B1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;

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Region: chr22:24376133..24384680 View in gBrowse