ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MGAT1
Previous Symbol	MGAT, GLYT1
Symbol Alias	GNT-1, GLCNAC-TI
Approved Name	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Location	5q35.3
Position	chr5:180217541-180242652, -1
External Links	HGNC: 7044 Entrez Gene: 4245 Ensembl: ENSG00000131446 UCSC: uc003mmg.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_14	chr5:178157153-180497731 (NCBI36 / hg18)	2340579	5q35.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006049	UDP-N-acetylglucosamine catabolic process	biological process	IEA	1
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0001701	in utero embryonic development	biological process	IEA	39
GO:0018279	protein N-linked glycosylation via asparagine	biological process	TAS	27
GO:0008375	acetylglucosaminyltransferase activity	molecular function	TAS[1702225]	2
GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	molecular function	IEA	1
GO:0044267	cellular protein metabolic process	biological process	TAS	78
GO:0046872	metal ion binding	molecular function	IEA	200
GO:0005975	carbohydrate metabolic process	biological process	TAS[1702225]	59
GO:0006486	protein glycosylation	biological process	TAS[1702225]	17
GO:0043687	post-translational protein modification	biological process	TAS	42
GO:0000139	Golgi membrane	cellular component	TAS	106

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01030	Glycan structures - biosynthesis 1	25
hsa00510	N-Glycan biosynthesis	10

Genes shared at least 5 GO terms with MGAT1 (count: 11)

Gene Symbol	Pathway Count	Pathway List
B4GALT6	7	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; metal ion binding; carbohydrate metabolic process; post-translational protein modification; Golgi membrane;
B4GALT4	7	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; metal ion binding; carbohydrate metabolic process; post-translational protein modification; Golgi membrane;
LMAN1	6	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; metal ion binding; post-translational protein modification; Golgi membrane;
MAN2A2	6	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; carbohydrate metabolic process; post-translational protein modification; Golgi membrane;
MGAT4B	6	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; metal ion binding; post-translational protein modification; Golgi membrane;
FURIN	5	integral to membrane; cellular protein metabolic process; metal ion binding; post-translational protein modification; Golgi membrane;
B3GAT1	5	integral to membrane; metal ion binding; carbohydrate metabolic process; protein glycosylation; Golgi membrane;
MAN1A1	5	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; Golgi membrane;
ALG1	5	integral to membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; protein glycosylation; post-translational protein modification;
ST3GAL4	5	protein N-linked glycosylation via asparagine; cellular protein metabolic process; carbohydrate metabolic process; post-translational protein modification; Golgi membrane;
ST8SIA3	5	protein N-linked glycosylation via asparagine; cellular protein metabolic process; protein glycosylation; post-translational protein modification; Golgi membrane;

Genes shared at least 2 KEGG pathways with MGAT1 (count: 9)

Gene Symbol	Pathway Count	Pathway List
ALG1	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
DPAGT1	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
ALG10	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
GANAB	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
ALG2	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
MGAT4B	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
ALG8	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
MAN1A1	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;
ALG9	2	Glycan structures - biosynthesis 1; N-Glycan biosynthesis;

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Region: chr5:180217541..180242652 View in gBrowse