ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ST8SIA3
Previous Symbol	SIAT8C
Approved Name	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Previous Name	sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase)
Name Alias	ST8Sia III
Location	18q21.31
Position	chr18:55019721-55036162, +
External Links	HGNC: 14269 Entrez Gene: 51046 Ensembl: ENSG00000177511 UCSC: uc002lgn.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q21.31-21.32	chr18:53800000-59000000	1 (1/0/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000139	Golgi membrane	Cellular Component		95
GO:0006491	N-glycan processing	Biological Process	IDA[10766765]	2
GO:0006486	protein glycosylation	Biological Process	IDA[10766765]	15
GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	Molecular Function	IDA[9826427]	1
GO:0001574	ganglioside biosynthetic process	Biological Process	IDA[10766765]	1
GO:0018279	protein N-linked glycosylation via asparagine	Biological Process		24
GO:0009311	oligosaccharide metabolic process	Biological Process	IDA[10766765]	2
GO:0009100	glycoprotein metabolic process	Biological Process	IDA[9826427]	2
GO:0006688	glycosphingolipid biosynthetic process	Biological Process	TAS[9073076]	2
GO:0044267	cellular protein metabolic process	Biological Process		64
GO:0043687	post-translational protein modification	Biological Process		37
GO:0033691	sialic acid binding	Molecular Function	IC[9826427]	1
GO:0030173	integral to Golgi membrane	Cellular Component		8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ST8SIA3 (count: 3)

Gene Symbol	Pathway Count	Pathway List
MGAT1	5	Golgi membrane; protein glycosylation; protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification;
MGAT4B	5	Golgi membrane; N-glycan processing; protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification;
ST3GAL4	5	Golgi membrane; protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; integral to Golgi membrane;

Genes shared at least 2 KEGG pathways with ST8SIA3 (count: 0)

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Region: chr18:55019721..55036162 View in gBrowse