ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007229
Name integrin-mediated signaling pathway
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ITGA1 integrin, alpha 1 5q11.1 2(0/2/0) IEA
PRKD1 protein kinase D1 14q11 1(0/1/0) TAS
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 17p13 1(0/0/1) IEA
ITGA11 integrin, alpha 11 15q22.3-q23 1(0/0/1) IEA

Genes from other sources Help (count: 6)

Approved Symbol Approved Name Source Evidence[PMID]
SYK spleen tyrosine kinase Mapped by significant region ISS; NAS[12885943]
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) Mapped by LD-proxy IEA
ILK integrin-linked kinase Mapped by CNV IDA[9366252]; NAS
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) Mapped by CNV IEA
CTGF connective tissue growth factor Mapped by significant region IEA
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region IDA[8649368]