ADHDgene Database

Gene Report

Basic Info

Approved Symbol	AATK
Symbol Alias	AATYK, KIAA0641, LMTK1, LMR1, AATYK1
Approved Name	apoptosis-associated tyrosine kinase
Name Alias	lemur tyrosine kinase 1
Location	17q25.3
Position	chr17:79091095-79139872, -
External Links	HGNC: 21 Entrez Gene: 9625 Ensembl: ENSG00000181409 UCSC: uc010dia.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 6)

rs_ID	Location	Functional Annotation
rs1801833	Chr17:79091353(Fwd)	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant
rs8073904	Chr17:79095144(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; synonymous_variant; upstream_gene_variant
rs6565535	Chr17:79090448(Fwd)	3_prime_UTR_variant; downstream_gene_variant
rs8071392	Chr17:79091103(Fwd)	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant
rs4969391	Chr17:79089590(Fwd)	3_prime_UTR_variant; downstream_gene_variant; missense_variant; nc_transcript_variant; non_coding_exon_variant
rs4076427	Chr17:79087537(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0046777	protein autophosphorylation	Biological Process		23
GO:0016021	integral to membrane	Cellular Component		845
GO:0048471	perinuclear region of cytoplasm	Cellular Component		87
GO:0005524	ATP binding	Molecular Function		228
GO:0005515	protein binding	Molecular Function	IPI[14521924]	910
GO:0006915	apoptotic process	Biological Process		111
GO:0005739	mitochondrion	Cellular Component		183
GO:0004674	protein serine/threonine kinase activity	Molecular Function		61
GO:0004713	protein tyrosine kinase activity	Molecular Function		10

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AATK (count: 7)

Gene Symbol	Pathway Count	Pathway List
ERBB2	6	protein autophosphorylation; integral to membrane; perinuclear region of cytoplasm; ATP binding; protein binding; protein tyrosine kinase activity;
MAP3K11	5	protein autophosphorylation; ATP binding; protein binding; protein serine/threonine kinase activity; protein tyrosine kinase activity;
NEK6	5	protein autophosphorylation; ATP binding; protein binding; apoptotic process; protein serine/threonine kinase activity;
PAK1	5	protein autophosphorylation; ATP binding; protein binding; apoptotic process; protein serine/threonine kinase activity;
PRKD1	5	protein autophosphorylation; ATP binding; protein binding; apoptotic process; protein serine/threonine kinase activity;
STK16	5	protein autophosphorylation; perinuclear region of cytoplasm; ATP binding; protein binding; protein serine/threonine kinase activity;
MAPK1	5	ATP binding; protein binding; apoptotic process; mitochondrion; protein serine/threonine kinase activity;

Genes shared at least 2 KEGG pathways with AATK (count: 0)

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Region: chr17:79091095..79139872 View in gBrowse