ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TSSK2
Previous Symbol	STK22B
Symbol Alias	SPOGA2, FLJ38613
Approved Name	testis-specific serine kinase 2
Previous Name	serine/threonine kinase 22B (spermiogenesis associated)
Location	22q11.21
Position	chr22:19118321-19120136, +
External Links	HGNC: 11401 Entrez Gene: 23617 Ensembl: ENSG00000206203 UCSC: uc002zow.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_40	chr22:17257787-19792353 (NCBI36 / hg18)	2534567	22q11.21	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006468	protein phosphorylation	Biological Process		53
GO:0005814	centriole	Cellular Component		11
GO:0007286	spermatid development	Biological Process		11
GO:0007275	multicellular organismal development	Biological Process		71
GO:0046777	protein autophosphorylation	Biological Process		23
GO:0042802	identical protein binding	Molecular Function	IPI[15044604]	70
GO:0001669	acrosomal vesicle	Cellular Component		9
GO:0000287	magnesium ion binding	Molecular Function		28
GO:0005515	protein binding	Molecular Function	IPI[15044604]	910
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA[18533145]	61
GO:0005737	cytoplasm	Cellular Component		690
GO:0005524	ATP binding	Molecular Function		228

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TSSK2 (count: 19)

Gene Symbol	Pathway Count	Pathway List
MAP3K11	7	protein phosphorylation; protein autophosphorylation; identical protein binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
NEK6	7	protein phosphorylation; protein autophosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
PAK1	7	protein phosphorylation; protein autophosphorylation; identical protein binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
SIK2	7	protein phosphorylation; protein autophosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
CDC42BPG	6	protein phosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
MARK2	6	protein phosphorylation; protein autophosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; ATP binding;
RPS6KA4	6	protein phosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
SIK3	6	protein phosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
STK36	6	protein phosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
TSSK4	6	protein phosphorylation; multicellular organismal development; magnesium ion binding; protein binding; protein serine/threonine kinase activity; ATP binding;
PRKD1	6	protein autophosphorylation; identical protein binding; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
ERBB2	5	protein phosphorylation; protein autophosphorylation; identical protein binding; protein binding; ATP binding;
FES	5	protein phosphorylation; multicellular organismal development; protein autophosphorylation; cytoplasm; ATP binding;
GSK3B	5	protein phosphorylation; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
ILK	5	protein phosphorylation; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
LATS1	5	protein phosphorylation; magnesium ion binding; protein binding; protein serine/threonine kinase activity; ATP binding;
PRKCB	5	protein phosphorylation; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;
WNK2	5	protein phosphorylation; protein autophosphorylation; protein serine/threonine kinase activity; cytoplasm; ATP binding;
SMG1	5	protein autophosphorylation; protein binding; protein serine/threonine kinase activity; cytoplasm; ATP binding;

Genes shared at least 2 KEGG pathways with TSSK2 (count: 0)

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Region: chr22:19118321..19120136 View in gBrowse