ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TSSK4
Previous Symbol	C14orf20, STK22E
Approved Name	testis-specific serine kinase 4
Previous Name	serine/threonine kinase 22E
Name Alias	chromosome 14 open reading frame 20
Location	14q11.2
Position	chr14:24674926-24677454, +
External Links	HGNC: 19825 Entrez Gene: 283629 Ensembl: ENSG00000139908 UCSC: uc001wng.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA[15964553]	61
GO:0000287	magnesium ion binding	Molecular Function	IDA[15964553]	28
GO:0005515	protein binding	Molecular Function		910
GO:0005524	ATP binding	Molecular Function	IDA[15964553]	228
GO:0006468	protein phosphorylation	Biological Process	IDA[15964553]	53
GO:0007275	multicellular organismal development	Biological Process		71
GO:0007283	spermatogenesis	Biological Process		35
GO:0030154	cell differentiation	Biological Process		51
GO:0032793	positive regulation of CREB transcription factor activity	Biological Process	IDA[15964553]	6

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TSSK4 (count: 9)

Gene Symbol	Pathway Count	Pathway List
RPS6KA4	6	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation; positive regulation of CREB transcription factor activity;
TSSK2	6	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation; multicellular organismal development;
CDC42BPG	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
LATS1	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
MARK2	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
NEK6	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
SIK2	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
SIK3	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;
STK36	5	protein serine/threonine kinase activity; magnesium ion binding; protein binding; ATP binding; protein phosphorylation;

Genes shared at least 2 KEGG pathways with TSSK4 (count: 0)

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Region: chr14:24674926..24677454 View in gBrowse