ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SIK3
Symbol Alias	FLJ12240, L19, KIAA0999, QSK
Approved Name	SIK family kinase 3
Location	11q23.3
Position	chr11:116714118-116969137, -
External Links	HGNC: 29165 Entrez Gene: 23387 Ensembl: ENSG00000160584 UCSC: uc001ppy.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000287	magnesium ion binding	Molecular Function	IDA[14976552]	28
GO:0006468	protein phosphorylation	Biological Process	IDA[14976552]	53
GO:0005524	ATP binding	Molecular Function	IDA[14976552]	228
GO:0005737	cytoplasm	Cellular Component		690
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA[14976552]	61
GO:0005515	protein binding	Molecular Function	IPI[16306228]	910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SIK3 (count: 14)

Gene Symbol	Pathway Count	Pathway List
CDC42BPG	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
NEK6	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
RPS6KA4	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
SIK2	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
STK36	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
TSSK2	6	magnesium ion binding; protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
LATS1	5	magnesium ion binding; protein phosphorylation; ATP binding; protein serine/threonine kinase activity; protein binding;
MARK2	5	magnesium ion binding; protein phosphorylation; ATP binding; protein serine/threonine kinase activity; protein binding;
TSSK4	5	magnesium ion binding; protein phosphorylation; ATP binding; protein serine/threonine kinase activity; protein binding;
GSK3B	5	protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
ILK	5	protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
MAP3K11	5	protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
PAK1	5	protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;
PRKCB	5	protein phosphorylation; ATP binding; cytoplasm; protein serine/threonine kinase activity; protein binding;

Genes shared at least 2 KEGG pathways with SIK3 (count: 0)

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Region: chr11:116714118..116969137 View in gBrowse