ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GPSM2
Previous Symbol	DFNB82
Symbol Alias	LGN, Pins
Approved Name	G-protein signaling modulator 2
Previous Name	G-protein signalling modulator 2 (AGS3-like, C. elegans), "deafness, autosomal recessive 82"
Location	1p13.3
Position	chr1:109417972-109473044, +
External Links	HGNC: 29501 Entrez Gene: 29899 Ensembl: ENSG00000121957 UCSC: uc010ovc.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_1	chr1:109103606-109682244 (NCBI36 / hg18)	578639	1p13.3	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component		690
GO:0005938	cell cortex	Cellular Component		26
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	TAS[8973305]	72
GO:0000132	establishment of mitotic spindle orientation	Biological Process		7
GO:0005092	GDP-dissociation inhibitor activity	Molecular Function		2
GO:0005515	protein binding	Molecular Function	IPI[15537540]	910
GO:0005634	nucleus	Cellular Component		770
GO:0042802	identical protein binding	Molecular Function	IPI[15537540]	70
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	Biological Process		5
GO:0060487	lung epithelial cell differentiation	Biological Process		2
GO:0045177	apical part of cell	Cellular Component		12

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GPSM2 (count: 8)

Gene Symbol	Pathway Count	Pathway List
NUMA1	7	nucleolus; cytoplasm; establishment of mitotic spindle orientation; protein binding; nucleus; lung epithelial cell differentiation; apical part of cell;
PAFAH1B1	6	nucleolus; cytoplasm; cell cortex; establishment of mitotic spindle orientation; protein binding; nucleus;
ATXN1	5	nucleolus; cytoplasm; protein binding; nucleus; identical protein binding;
BAIAP2	5	nucleolus; cytoplasm; protein binding; nucleus; identical protein binding;
PRC1	5	nucleolus; cytoplasm; protein binding; nucleus; identical protein binding;
TRIM5	5	nucleolus; cytoplasm; protein binding; nucleus; identical protein binding;
PRKD1	5	cytoplasm; cell cortex; protein binding; nucleus; identical protein binding;
SNCA	5	cytoplasm; cell cortex; protein binding; nucleus; identical protein binding;

Genes shared at least 2 KEGG pathways with GPSM2 (count: 0)

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Region: chr1:109417972..109473044 View in gBrowse