ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0030424
Name	axon
Type	Cellular Component
No. of Genes in ADHDgene	35
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 35)

Literature-origin genes (count: 9)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)	IDA[12958153]
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7p11	6(5/1/0)
GRM7	glutamate receptor, metabotropic 7	3p26-p25	1(1/0/0)
CNTN4	contactin 4	3p26.3	1(1/0/0)	NAS[14571131]
HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	5p12	1(0/1/0)
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	4q21.3-q22	1(0/1/0)	IDA[12958153]
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	3p25-p24	1(0/1/0)
CTNNA2	catenin (cadherin-associated protein), alpha 2	2p12-p11.1	2(1/1/0)

Genes from other sources (count: 26)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CANX	calnexin	Mapped by CNV
ROBO3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	Mapped by significant region
IGHMBP2	immunoglobulin mu binding protein 2	Mapped by CNV; Mapped by significant region
ACHE	acetylcholinesterase	Mapped by PBA pathway
KIRREL3	kin of IRRE like 3 (Drosophila)	Mapped by significant region
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	Mapped by significant region
CNTNAP2	contactin associated protein-like 2	Mapped by CNV
PTPRK	protein tyrosine phosphatase, receptor type, K	Mapped by CNV; Mapped by significant region
CADM1	cell adhesion molecule 1	Mapped by significant region
PDE2A	phosphodiesterase 2A, cGMP-stimulated	Mapped by significant region
EPHA5	EPH receptor A5	Mapped by CNV; Mapped by significant region
TUBB3	tubulin, beta 3	Mapped by significant region
BACE1	beta-site APP-cleaving enzyme 1	Mapped by significant region
LLGL1	lethal giant larvae homolog 1 (Drosophila)	Mapped by significant region
KATNB1	katanin p80 (WD repeat containing) subunit B 1	Mapped by PBA pathway
MTMR2	myotubularin related protein 2	Mapped by significant region
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	Mapped by significant region
FAM168B	family with sequence similarity 168, member B	Mapped by CNV; Mapped by significant region
IRX3	iroquois homeobox 3	Mapped by CNV
OMP	olfactory marker protein	Mapped by significant region
MAPT	microtubule-associated protein tau	Mapped by LD-proxy; Mapped by PBA pathway	IDA[8642405]
CA2	carbonic anhydrase II	Mapped by CNV
HEPACAM	hepatic and glial cell adhesion molecule	Mapped by significant region
FKBP15	FK506 binding protein 15, 133kDa	Mapped by significant region
TXN	thioredoxin	Mapped by significant region
NCAM1	neural cell adhesion molecule 1	Mapped by significant region