ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NEUROD2
Symbol Alias	NDRF, bHLHa1
Approved Name	neurogenic differentiation 2
Location	17q12
Position	chr17:37760021-37764196, -
External Links	HGNC: 7763 Entrez Gene: 4761 Ensembl: ENSG00000171532 UCSC: uc002hry.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 3)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	TAS[8816493]	42
GO:0007399	nervous system development	Biological Process	TAS[8816493]	54
GO:0008306	associative learning	Biological Process		5
GO:0016567	protein ubiquitination	Biological Process		41
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	TAS[8816493]	132
GO:0003714	transcription corepressor activity	Molecular Function		29
GO:0005634	nucleus	Cellular Component		770
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0048666	neuron development	Biological Process		7
GO:0050850	positive regulation of calcium-mediated signaling	Biological Process		7
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	Biological Process		11
GO:0070888	E-box binding	Molecular Function		4
GO:0021695	cerebellar cortex development	Biological Process		2
GO:0031915	positive regulation of synaptic plasticity	Biological Process		2
GO:0045666	positive regulation of neuron differentiation	Biological Process		13
GO:0046982	protein heterodimerization activity	Molecular Function		68
GO:2000297	negative regulation of synapse maturation	Biological Process		1
GO:0090129	positive regulation of synapse maturation	Biological Process		2
GO:0071277	cellular response to calcium ion	Biological Process		4
GO:0071257	cellular response to electrical stimulus	Biological Process		2
GO:0001662	behavioral fear response	Biological Process		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NEUROD2 (count: 5)

Gene Symbol	Pathway Count	Pathway List
HIRA	5	regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; nucleus; transcription, DNA-dependent;
KDM1A	5	regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; positive regulation of sequence-specific DNA binding transcription factor activity;
SMARCB1	5	regulation of transcription from RNA polymerase II promoter; nervous system development; nucleus; transcription, DNA-dependent; positive regulation of sequence-specific DNA binding transcription factor activity;
TRIM22	5	protein ubiquitination; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; nucleus; transcription, DNA-dependent;
DRAP1	5	sequence-specific DNA binding transcription factor activity; transcription corepressor activity; nucleus; transcription, DNA-dependent; protein heterodimerization activity;

Genes shared at least 2 KEGG pathways with NEUROD2 (count: 0)

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Region: chr17:37760021..37764196 View in gBrowse