ADHDgene Database

Gene Report

Basic Info

Approved Symbol	EED
Symbol Alias	WAIT-1, HEED
Approved Name	embryonic ectoderm development
Name Alias	WD protein associating with integrin cytoplasmic tails 1
Location	11q14.2-q22.3
Position	chr11:85955586-85989781, +
External Links	HGNC: 3188 Entrez Gene: 8726 Ensembl: ENSG00000074266 UCSC: uc001pbp.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	NAS[9584199]	64
GO:0045120	pronucleus	Cellular Component		1
GO:0035098	ESC/E(Z) complex	Cellular Component	IDA[15385962]	1
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0042802	identical protein binding	Molecular Function	IPI[11124122]	70
GO:0042054	histone methyltransferase activity	Molecular Function	IDA[15385962]	1
GO:0005634	nucleus	Cellular Component	NAS[9584199]	770
GO:0006349	regulation of gene expression by genetic imprinting	Biological Process		3
GO:0003682	chromatin binding	Molecular Function		48
GO:0005515	protein binding	Molecular Function		910
GO:0001739	sex chromatin	Cellular Component		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with EED (count: 8)

Gene Symbol	Pathway Count	Pathway List
ATXN1	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; identical protein binding; nucleus; protein binding;
CBX3	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; identical protein binding; nucleus; protein binding;
HINFP	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; chromatin binding; protein binding;
KDM1A	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; chromatin binding; protein binding;
MEN1	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleus; chromatin binding; protein binding;
RELA	5	negative regulation of transcription, DNA-dependent; identical protein binding; nucleus; chromatin binding; protein binding;
ZBTB16	5	negative regulation of transcription, DNA-dependent; transcription, DNA-dependent; identical protein binding; nucleus; protein binding;
RNF2	5	transcription, DNA-dependent; nucleus; chromatin binding; protein binding; sex chromatin;

Genes shared at least 2 KEGG pathways with EED (count: 0)

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Region: chr11:85955586..85989781 View in gBrowse