ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LAMA3
Previous Symbol	LAMNA
Symbol Alias	nicein-150kDa, kalinin-165kDa, BM600-150kDa, epiligrin
Approved Name	laminin, alpha 3
Previous Name	"laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)"
Location	18q11.2
Position	chr18:21269407-21535030, 1
External Links	HGNC: 6483 Entrez Gene: 3909 Ensembl: ENSG00000053747 UCSC: uc002kuq.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045995	regulation of embryonic development	biological process	IEA	3
GO:0005606	laminin-1 complex	cellular component	IEA	3
GO:0005576	extracellular region	cellular component	TAS	267
GO:0031581	hemidesmosome assembly	biological process	TAS	3
GO:0034329	cell junction assembly	biological process	TAS	18
GO:0030155	regulation of cell adhesion	biological process	IEA	8
GO:0005102	receptor binding	molecular function	IEA	64
GO:0008544	epidermis development	biological process	TAS[8586427]	12
GO:0005604	basement membrane	cellular component	TAS[8586427]	13
GO:0030334	regulation of cell migration	biological process	IEA	10
GO:0007155	cell adhesion	biological process	IEA	99
GO:0005198	structural molecule activity	molecular function	NAS[8586427]	34
GO:0005610	laminin-5 complex	cellular component	IEA	2

Gene related KEGG pathways (count: 4)

ID	Name	No. of Genes in ADHDgene
hsa04512	ECM-receptor interaction	13
hsa04510	Focal adhesion	40
hsa05222	Small cell lung cancer	17
hsa01430	Cell Communication	23

Genes shared at least 5 GO terms with LAMA3 (count: 3)

Gene Symbol	Pathway Count	Pathway List
LAMA2	9	regulation of embryonic development; laminin-1 complex; extracellular region; regulation of cell adhesion; receptor binding; basement membrane; regulation of cell migration; cell adhesion; structural molecule activity;
LAMC2	6	extracellular region; hemidesmosome assembly; cell junction assembly; epidermis development; cell adhesion; laminin-5 complex;
LAMC1	5	laminin-1 complex; extracellular region; hemidesmosome assembly; basement membrane; cell adhesion;

Genes shared at least 2 KEGG pathways with LAMA3 (count: 15)

Gene Symbol	Pathway Count	Pathway List
FN1	4	ECM-receptor interaction; Focal adhesion; Small cell lung cancer; Cell Communication;
LAMC2	4	ECM-receptor interaction; Focal adhesion; Small cell lung cancer; Cell Communication;
LAMA2	4	ECM-receptor interaction; Focal adhesion; Small cell lung cancer; Cell Communication;
LAMC1	4	ECM-receptor interaction; Focal adhesion; Small cell lung cancer; Cell Communication;
ITGA2	3	ECM-receptor interaction; Focal adhesion; Small cell lung cancer;
TNN	3	ECM-receptor interaction; Focal adhesion; Cell Communication;
TNC	3	ECM-receptor interaction; Focal adhesion; Cell Communication;
TNR	3	ECM-receptor interaction; Focal adhesion; Cell Communication;
ITGA11	2	ECM-receptor interaction; Focal adhesion;
ITGA1	2	ECM-receptor interaction; Focal adhesion;
BIRC2	2	Focal adhesion; Small cell lung cancer;
PIK3R1	2	Focal adhesion; Small cell lung cancer;
PIK3CG	2	Focal adhesion; Small cell lung cancer;
BIRC3	2	Focal adhesion; Small cell lung cancer;
CCND1	2	Focal adhesion; Small cell lung cancer;

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Region: chr18:21269407..21535030 View in gBrowse