ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol PPP2R2C
Symbol Alias PR52, IMYPNO, MGC33570, PR55G
Approved Name protein phosphatase 2, regulatory subunit B, gamma
Previous Name "protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform", "protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform"
Name Alias "PP2A subunit B isoform gamma"
Location 4p16.1
Position chr4:6322305-6565327, -1
External Links HGNC: 9306
Entrez Gene: 5522
Ensembl: ENSG00000074211
UCSC: uc003gja.3
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Jacob, C., 2012 In neither the family-based, nor the adult ADHD case-control samples, significant associations on the haplotype level were detected (best p value = 0.22). There is evidence that allelic variation in PPP2R2C may be associated with a variety of personality traits and ADHD per se. Nevertheless, as all those conditions are comorbid, PPP2R2C might reflect a common underlying neurobiological risk factor. Significant

Gene related SNPs (count: 37)

Literature-origin SNPs (count: 4)

LD-proxies (count: 33)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 3)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 3)


Gene related KEGG pathways (count: 4)

Genes shared at least 5 GO terms with PPP2R2C (count: 0)

Genes shared at least 2 KEGG pathways with PPP2R2C (count: 7)

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Region: chr4:6322305..6565327 View in gBrowse
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