ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol NTF3
Symbol Alias NGF2
Approved Name neurotrophin 3
Location 12p13
Position chr12:5541278-5630702, 1
External Links HGNC: 8023
Entrez Gene: 4908
Ensembl: ENSG00000185652
UCSC: uc001qnk.4
No. of Studies 4 (significant: 1; non-significant: 3; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 4)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Ribases M, 2008 a four-marker haplotype (rs4074967-rs6332-rs6489630-rs7956189) global P-value=2.3e-04, Best Haplotype P-value=2.1e-05, adjusted P-value=1.0e-04, OR=1.48 (1.20-1.84) in children; Haplotype-Specific(TACA) P-value=2.1e-05; OR(CI)=1.6 (1.28-2.00), Haplotype-Specific (TGCA) P-value=3.0e-04; OR(CI)=1.48 (1.20-1.84) in children Significant
Syed Z, 2007 No evidence of association was seen. Non-significant
Pazvantoglu, O.,2013 The SNP in the genes NTF3 (rs6332) was not associated with ADHD Non-significant
Cho SC, 2010(b) no significant differences in the genotype frequencies and the haplotype analysis; in the case-control and family-based analyses, NTF3 was not significantly associated with ADHD Non-significant

Gene related SNPs (count: 22)

Literature-origin SNPs (count: 5)

LD-proxies (count: 17)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 38)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 38)

Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with NTF3 (count: 21)

Genes shared at least 2 KEGG pathways with NTF3 (count: 0)

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Region: chr12:5541278..5630702 View in gBrowse
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