ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol CLOCK
Symbol Alias KIAA0334, KAT13D, bHLHe8
Approved Name clock circadian regulator
Previous Name "clock (mouse) homolog", "clock homolog (mouse)"
Location 4q12
Position chr4:56294070-56413305, -1
External Links HGNC: 2082
Entrez Gene: 9575
Ensembl: ENSG00000134852
UCSC: uc003hba.2
No. of Studies 2 (significant: 2; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 2)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Xu X, 2010 T allele of rs1801260 was significantly over-transmitted in the Taiwanese samples and combined samples even after Bonferroni correction, possible involvement of CLOCK in susceptibility to ADHD Significant
Kissling C, 2008 rs1801260 of a gene within the circadian 'clock' mechanism is a direct or linked contributing factor in adult ADHD Significant

Gene related SNPs (count: 17)

Literature-origin SNPs (count: 1)

LD-proxies (count: 16)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 23)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 23)


Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with CLOCK (count: 26)

Genes shared at least 2 KEGG pathways with CLOCK (count: 0)

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Region: chr4:56294070..56413305 View in gBrowse
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