ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0046983
Name protein dimerization activity
Type molecular function
No. of Genes in ADHDgene  28
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 28)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CLOCK clock circadian regulator 4q12 2(2/0/0) IEA
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA[12072434]
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) IEA
HES6 hes family bHLH transcription factor 6 2q37.3 1(0/1/0) IEA
NEUROD6 neuronal differentiation 6 7p15.1 1(0/1/0) IEA
NPAS3 neuronal PAS domain protein 3 14q13.1 1(1/0/0) IEA

Genes from other sources Help (count: 22)

Approved Symbol Approved Name Source Evidence[PMID]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IDA[15790808]
SCAND3 SCAN domain containing 3 Mapped by LD-proxy IEA
WWOX WW domain containing oxidoreductase Mapped by significant region TAS[10786676]
OLIG3 oligodendrocyte transcription factor 3 Mapped by significant region IEA
EBF1 early B-cell factor 1 Mapped by significant region IEA
TCF21 transcription factor 21 Mapped by CNV; Mapped by significant region ISS
MYO7A myosin VIIA Mapped by significant region RCA[8622919]
GPR139 G protein-coupled receptor 139 Mapped by significant region IEA
PDCD6 programmed cell death 6 Mapped by significant region IPI[11883899]
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region IEA
PRDX5 peroxiredoxin 5 Mapped by significant region IDA[15046979]
NLGN1 neuroligin 1 Mapped by CNV ISS
NPAS2 neuronal PAS domain protein 2 Mapped by CNV IEA
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) Mapped by significant region IEA
TBX1 T-box 1 Mapped by CNV TAS[17273972]
TAL2 T-cell acute lymphocytic leukemia 2 Mapped by significant region IEA
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 Mapped by CNV IDA
POU2F3 POU class 2 homeobox 3 Mapped by significant region IEA
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 Mapped by significant region IEA
SPEF2 sperm flagellar 2 Mapped by significant region IEA
AHRR aryl-hydrocarbon receptor repressor Mapped by significant region IEA
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy NAS[12000754]