ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLC4A11
Previous Symbol	CHED2
Symbol Alias	dJ794I6.2, BTR1, NaBC1
Approved Name	solute carrier family 4, sodium borate transporter, member 11
Previous Name	corneal endothelial dystrophy 2 (autosomal recessive), "solute carrier family 4, sodium bicarbonate transporter-like, member 11"
Location	20p12
Position	chr20:3208063-3219887, -
External Links	HGNC: 16438 Entrez Gene: 83959 Ensembl: ENSG00000088836 UCSC: uc002wig.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_35	chr20:3036010-3839896 (NCBI Build 36.1 (hg18))	803887	20p13	Loss	De novo

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0015106	bicarbonate transmembrane transporter activity	Molecular Function	IDA[15525507]	1
GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	Biological Process		1
GO:0015701	bicarbonate transport	Biological Process	IDA[15525507]	8
GO:0015252	hydrogen ion channel activity	Molecular Function	IDA[15525507]	1
GO:0016021	integral to membrane	Cellular Component		845
GO:0015992	proton transport	Biological Process	IDA[15525507]	6
GO:0030003	cellular cation homeostasis	Biological Process	IDA[15525507]	1
GO:0016323	basolateral plasma membrane	Cellular Component	TAS[15525507]	29
GO:0035725	sodium ion transmembrane transport	Biological Process	IDA[15525507]	4
GO:0035445	borate transmembrane transport	Biological Process	IDA[15525507]	1
GO:0046713	borate transport	Biological Process	IDA[15525507]	1
GO:0042044	fluid transport	Biological Process		1
GO:0046983	protein dimerization activity	Molecular Function		26
GO:0046715	borate transmembrane transporter activity	Molecular Function	IDA[15525507]	1
GO:0005452	inorganic anion exchanger activity	Molecular Function		6
GO:0006814	sodium ion transport	Biological Process	IDA[15525507]	9
GO:0005272	sodium channel activity	Molecular Function	IDA[15525507]	4
GO:0005351	sugar:hydrogen symporter activity	Molecular Function		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SLC4A11 (count: 0)

Genes shared at least 2 KEGG pathways with SLC4A11 (count: 0)

View in gBrowse

Region: chr20:3208063..3219887 View in gBrowse